|A Systematic Review of Lifestyle Modification in Adults with Non-Alcoholic Fatty Liver Disease|
C. Thoma, C. P. Day and M. I. Trenell, Newcastle University
This study reviews the causes of non-alcoholic fatty liver disease and the associated risk factor for type 2 diabetes and cardiovascular disease.
|Identification of Novel BACE-1 Inhibitors through an Advanced Structure-Based Virtual Screening Protocol|
Puneet Kacker, Angela De Simone, Matteo Masetti, Giovanni Bottegoni, Vincenza Andrisano, Andrea Cavalli
This study assesses the influence of different ligand chemotypes on the protonation state of the catalytic dyad.
|Cytotoxicity Screen of Mangiferin and its Major Metabolite Norathyriol in Human Tumor Cell Lines|
Souza, J.R.R., Feitosa, J.P.A., Ricardo, N.M.P.S, Trevisan, M.T.S., Frei, E., Ulrich C.M., Owen, R.W.
Many natural products are available worldwide as potential chemoprotective agents against commonly occurring cancers, for example Mangiferin which has low bioavailability and is thought to be mainly available in the colon.
|Rapid PCR for Integration in Sample-to-answer Analysis Platforms|
S. Brunklaus, T.E. Hansen-Hagge, J. Erwes, J. Höth, M. Jung, D. Latta, X. Strobach, C. Winkler, T. Röser, M. Ritzi-Lehnert, K.S. Drese
This poster describes how molecular testing at the point-of-care can increase time to results and yield rather specific information, concentrating on PCR on a chip layout which proves to be fast and robust.
|Lab-on-a-Chip System for Detection of Mycotoxins in Animal Feed|
S. Brunklaus, V. Stein, M. Jakubowski, M. Ritzi-Lehnert, K.S. Drese, R. Colasanto, P. Poletti
This poster introduces an automated Lab-on-a-Chip system for reliable quantitative testing of mycotoxin contamination of animal feed developed in the framework of the EU-funded project micro- FLUID.
|Polarized Cell Expansion and Heterochronic Shift in Angiosperm Spermatogenesis|
Said Hafidh, Katarina Breznenova, Jana Fecikova, Vera Capkova and David Honys
This study evaluates genetic factors and common pathways in polarized cell-tip expansion.
|UPLC-MS/MS for the Screening, Confirmation and Quantification of 32 Drugs Illegally Added to Herbal/Dietary Supplements for the Enhancement of Male Sexual Performance|
Salman Azimi, Nayan Mistry and Michelle Wood
This poster outlines development of a novel screening method that is suitable for both the detection of known and unknown ED drugs and analogues. Comprehensive spectral data is collected and automatically compared to a prepared library if known drugs.
|Laser Welded Microfluidic Plasma Seperation Unit with On-Chip Pressure Conversion|
Thomas Brettschneider, Christian Dorrer, Roland Zengerle and Martina Daub
This poster shows how microfluidic components for the separation of plasma from full blood can be cost-effective, with reliable processing and the production of quality plasma.
|One Pot Method for the Simultaneous Synthesis and Anchoring of Organic Monolith Inside COC Microchip Channel|
Y. Ladner, A. Bruchet, V. Dugas, J. Randon, G. Crétier, K. Faure
Study shows monolith synthesis in COC microchip, including: the influence of BME concentration on performances; the separations of primary amines.