|Stealth-Adapted Viruses and Viteria: Insights into Virus Construction, Replication and Potential Therapies|
W. John Martin
There is an increasing incidence of diseases with accompanying signs and symptoms of brain damage. These include neurological and psychiatric illnesses, childhood behavioral disorders, and such common conditions as chronic fatigue, Gulf War Syndrome, so-called “chronic Lyme disease”, and many cancers. Altogether, these diseases have an enormous social impact.
|A New Approach to Increase Yields and Improve Functionality of Recombinant Proteins|
Antti Vasala, BioSilta Oy, Oulu, Finland
The ability to express and extract fully functional proteins in sufficient quantities from bacterial cultures is a prerequisite for many projects in which recombinant proteins are required for structural studies, functional characterization, as assay components or for other applications. However, low yield, poor solubility and lack of functionality are often associated with, what should be, a routine procedure.
|Functional Monoliths for Flow Processes by RAFT Polymerisation|
Kristine J. Barlow, Victor Bernabeu, Xiaojuan Hao, Timothy C. Hughes, Oliver E. Hutt, Anastasios Polyzos, Kathleen A. Turner, Graeme Moad
Polymeric monoliths have recently emerged as a new class of solid supports for stoichiometric and catalytic reactions in continuous flow synthesis.
|Low-cost “Plug & Play” On-Chip Valve and Pump for Thermoplastic Microfluidics|
Mousavi Shaegh Seyed Ali, Wang Zhenfeng, Toh Guek Geok, Soh Yong Chear
Scientists have developed a novel on-chip valving solution for thermoplastic microfluidic devices, which is reliable, easy to implement, and has low-cost fabrication.
|Novel Nucleosomics Serum Biomarkers for the Detection of Colorectal Cancer|
S Holdenrieder, Y Dharuman, J Standop, M Herzog, N Trimpop, K Hettwer, K Simon, Steffen Uhlig and Jake Micallef
As colorectal cancers are often detected at late tumor stages when prognosis of the patients is poor, powerful blood-based biomarkers are needed for earlier detection. In recent years it has become clear that epigenetic changes to chromatin and its constituent nucleosomes are associated with carcinogenesis and elevated levels of nucleosomes are present in the blood of cancer patients.
|Fingerprinting analytical strategy used for authentication of honey|
Oana Romina DINCAa,b, Roxana Elena IONETEa*, Raluca POPESCUa, Radu TAMAIANa, Diana COSTINELa, Gabriel Lucian RADUb
The goal of the current study is mainly to establish potential origin markers, and not to build a model for prediction. This research provides a database for comparison of honey samples from Romania with other honey samples from the world. Data on d13C, d18O and d2H of honey measured by IRMS together with the stable isotopes (deuterium by SNIF-NMR and carbon 13 - IRMS) in ethanol from fermented honeys were reported.
|Function of Protein Kinase C-1 in memory in Caenorhabditis elegans|
To study long lasting olfactory memory in C. elegans, we conditioned the nematodes to form an association between the odorant benzaldehyde and starvation.
|A novel DNA amplification method based on silicon microring resonator for rapid detection of genetic alteration in the point-of care (POC) field of cancers|
Nucleic acid testing plays a critical role in molecular diagnosis[1-2]. Due to the low amounts of DNA obtained in clinical samples, the amplification of DNA is an essential step in most NAT methods .
|Automated Quantitative Analysis of Ethanol, Glucose and NADH in the UV/VIS and Short NIR|
Process Analytical Technology currently becomes more and more important for food and pharmaceutical industry for example because of the increasing demand for more effective and efficient quality control. Therefore it is necessary to get timely and targeted responses of the different parameters in bioprocesses. To attain this aim, it is helpful to replace the conventional (manual) laboratory techniques with automated measuring processes via in-line probe.