Enzyme Coated Magnetic Nanoparticles For Use In Continous Flow Microfluidic Devices

Magnetic nanoparticles (MNPs) are widely used as bio molecule carriers providing higher reactive area and low diffusion limits, specific modifications enabling convenient handling within chip sized fluidic structures. Our infrastructure for the production of tailor made MNPs enables to optimize the particles for the use in a LoC platform. The novel platform incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.