Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>Products>This Product

MaxDiscovery™ Caspase-3 Fluorescence Detection Kit

Product Description
Caspase-3 is a ubiquitously-expressed cysteine protease involved in programmed cell death (apoptosis). In nonapoptotic cells, this enzyme exists as an inactive zymogen known as procaspase-3. Intracellular procaspase-3 is activated when cells are committed to die via apoptosis; induction of the cell death machinery eventually triggers activation of the zymogen by proteolytic cleavage of the zymogen to an active heterodimer comprised of 17 kDa and 12 kDa subunits. The active enzyme cleaves a number of intracellular protein targets important for cell survival. Therefore, monitoring caspase-3 enzyme activity is a fundamental means to measure apoptosis in cells. This assay is an important tool for apoptosis research as well as investigating the apoptotic effects of experimental drug formulations and cell transfection. The MaxDiscovery™ Caspase-3 Fluorescence Detection Kit is a fluorescence microplate-based assay to directly measure caspase-3 activation in cultured cells. This kit enables biomedical researchers to determine caspase-3 levels in cultured cells from a broad range of cell lines. The assay utilizes a simple, proven enzymatic assay to detect activated enzyme. Because caspase-3 is expressed in every cell type, the assay can be performed using any mammalian cell line.
Product MaxDiscovery™ Caspase-3 Fluorescence Detection Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 5810
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122

Scientific News
Lung Repair and Regeneration Gene Discovered
New role for hedgehog gene offers better understanding of lung disease.
How Cell Growth Triggers Cell Division
Researchers in Jan Skotheim's lab have discovered a previously unknown mechanism that controls how large cells grow, an insight that could one day provide insight into attacking diseases such as cancer.
Microbe Sleuth
Tanja Bosak examines how life and the Earth evolved in tandem during their early history together.
3 Ways Viruses Have Changed Science for the Better
Viruses are really good at what they do, and we’ve been able to harness their skills to learn about – and potentially improve – human health in several ways.
Restoring Vision with Stem Cells
Age-related macular degeneration (AMRD) could be treated by transplanting photoreceptors produced by the directed differentiation of stem cells, thanks to findings published today by Professor Gilbert Bernier of the University of Montreal and its affiliated Maisonneuve-Rosemont Hospital.
The Age of Humans Controlling Microbes
Engineered bacteria could soon be used to detect environmental toxins, treat diseases, and sustainably produce chemicals and fuels.
Mixed Up Cell Transportation Key Piece of ALS and Dementia Puzzle
Researchers from the University of Toronto are one step closer to solving this incredibly complex puzzle, offering hope for treatment.
Metabolomic Platform Reveals Fundamental Flaw in Common Lab Technology
A new study led by scientists at The Scripps Research Institute (TSRI) shows that a technology used in thousands of laboratories, called gas chromatography mass spectrometry (GC-MS), fundamentally alters the samples it analyzes.
Atriva Therapeutics GmbH Develops Innovative Flu Drug
Highly effective against seasonal and pandemic influenza.
New Gene Therapy for Vision Loss From a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Scroll Up
Scroll Down

Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos