One of the hurdles to delivering RNAi effectively includes being able to deliver siRNA into specific cells and organs. Using the T3™ Conjugation Kit, based on Bioo Scientific’s patent pending Targeted Transport Technology, scientists can administer siRNA to target cells and tissues using both in vivo and in vitro models. The T3 Conjugation Kit lets scientists deliver siRNA or miRNA into any cell type they want by conjugating the T3 carrier to an antibody that is specific to a receptor or other extracellular domain specific to the cell or tissue type they want to target. The T3 procedure does not require any prior modifications of the antibody or the RNAi agent and can be performed in a few simple steps. T3™ Conjugation Kit Procedure 1. Identify an antibody that is specific to a receptor specific to your targeted cell type 2. Conjugate the antibody to the T3 Carrier 3. Load the T3 Conjugate with siRNA or miRNA 4. Administer to animal or transfect cell lines 5. T3 Conjugate is taken up by targeted cells 6. The siRNA or miRNA is released inside the targeted cells Selected References: Goodchild, J (2011) Therapeutic Oligonucleotides: Methods and Protocols. Humana Press 1st Edition.