Asterand plc is the leading global provider of high quality, well characterized human tissue and human tissue-based research solutions to drug discovery scientists. (Our mission is to provide human-based solutions to accelerate the identification and validation of drug targets and enhance the selection of drug candidates with an increased likelihood of clinical success).
Asterand plc has a well established human tissue heritage, having been formed in 2006 through the merger of Asterand (founded 2000), a human tissue biorepository and Pharmagene (founded 1996) a human tissue-based drug discovery company. Our expertise has been further strengthened following the acquisition of BioSeek in February 2010. BioSeek (founded 2000) brings proprietary, primary cell-based models of human disease biology that provide early insight into human pharmacological and toxicological properties of compounds through comparison of resulting data profiles with an established and growing database of profiles for known compounds.
With this background and capability in human tissue procurement, characterization and research, Asterand is uniquely positioned to provide a comprehensive approach to meet the research needs of pharmaceutical, biotechnology and diagnositic companies, as well as academia. From our offices in Detroit, MI Royston, U.K. and San Francisco, CA, we have more than 100 employees focused on providing services and products to accelerate drug discovery research from target identification through to compound evaluation and drug safety.
Retractable Protein Nanoneedles The ability to control the transfer of molecules through cellular membranes is an important function in synthetic biology; a new study from researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) introduces a novel mechanical method for controlling release of molecules inside cells.Leukemia’s Surroundings Key to its Growth Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous.Common Cell Transformed into Master Heart Cell By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin—Madison have generated master heart cells — primitive progenitors that form the developing heart.‘Smelling’ Prostate Cancer A research team from the University of Liverpool and the University of the West of England (UWE Bristol) has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.Genetic Mutation that Prevents Diabetes Complications The most significant complications of diabetes include diabetic retinal disease, or retinopathy, and diabetic kidney disease, or nephropathy. Both involve damaged capillaries.A Crystal Clear View of Biomolecules Fundamental discovery triggers paradigm shift in crystallography.Could the Food we Eat Affect Our Genes? Almost all of our genes may be influenced by the food we eat, according to new research.NIH Seeks Research Applications to Study Zika in Pregnancy, Developing Fetus Institute has announced that the new effort seeks to understand virus effect on reproduction and child development.Iron in the Blood Could Cause Cell Damage Concentrations of iron similar to those delivered through standard treatments can trigger DNA damage within 10 minutes, when given to cells in the laboratory. Neanderthal DNA Influences Human Disease Risk Large-scale, evolutionary analysis compares genetic data alongside electronic health records.