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Custom made highly complex, domain libraries

Product Description
Our libraries are the most complex ones available on the market and our ULTImate cell-to-cell mating is the only screening technology that can screen them exhaustively. Should you not find your favourite library among our 60+ libraries, we would be happy to construct it for you.

Our ULTImate domain libraries are validated by extremely stringent quality controls:
- Verifying a complexity of at least 10 million independent, primary fragments in yeast for Random-Primed cDNA libraries. The complexity of the genomic libraries (constructed for organisms that contain no or few introns) depends on the size of the genome (e.g. 2 million genomic fragments for Helicobacter pylori library)
- Random sequencing of 192 clones to check for i) absence of contamination, ii) that ribosomal RNA, mitochondrial DNA and empty vectors represent less than 10% of the total sequences
- Verifying the viability and mating properties of the library-containing yeast cells, and defining the conditions to obtain the highest mating efficiency (Patent US No 6,187,535)
- Reproducing selected Y2H screen interactions available from the literature.

For more details, please go to:
Product Custom made highly complex, domain libraries
Company Hybrigenics Services SAS
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Hybrigenics Services SAS
3-5 Impasse Reille 75014 Paris France

Tel: +33 (0)1 58 10 38 29
Fax: +33 (0)1 58 10 38 48

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