Small Interfering RNA (siRNA)-mediated gene silencing is an exciting and valuable tool for studying gene function. However, most researchers are limited by their ability to test only a handful of chemically synthetic siRNAs due to high cost and lack of design guidance. Dicer siRNA Generation Kit allows cost-effective production of siRNAs targeted against entire gene sequences for efficient gene silencing. Harness the Natural Process. Most researchers purchase 3 to 8 chemically synthesized double-stranded siRNAs for each gene of interest to test whether they can get any strong gene silencing effect. This means synthesizing and processing 6 to 16 RNA oligonucleotides at a relatively high cost. The Dicer siRNA Generation Kits mimic the natural RNA interference process by using the recombinant human dicer enzyme to cleave in vitro transcribed dsRNA into a pool of 20 to 21-bp siRNAs.
Genlantis offers two different types of kits to generate siRNA: the original Dicer siRNA Generation Kits, and the more rapid Turbo Dicer siRNA Generation Kits. Additionally, multiple configurations and component kits of either the original or Turbo Dicer kits are offered to make these kits as convenient and cost effective as possible.
For the utmost in convenience and efficiency, Genlantis also offers one of the most widely-used and effective siRNA delivery reagents on the market, the GeneSilencer™ Transfection Reagent. The GeneSilencer reagent is provided as a prepackaged component of either Dicer siRNA generation kits, or it can be purchased separately in many different sizes and configurations. The GeneSilencer™ siRNA Transfection Reagent ensures efficient delivery of precious siRNA samples, no matter which method is used to produce these siRNAs.