Case Study Demonstrates Importance of MIQE for qPCR Data AnalysisPublished by Bio-Rad Laboratories, Inc. this case study demonstrates how real-time PCR can lead to erroneous conclusions if the key steps set out in the MIQE guidelines are not followed.
NanoInk Announces Launch of Contract Services Program for Live Single Cell Assay WorkService offering expected to advance research programs involved with toxicity assessment, high content screening, and cell-cell communication.
Hamilton Introduces Automated DNA Sample Enrichment SolutionSystem uses Roche 454 REM e liquid handling system to replace hours of manual work.
Roche’s Novel Tests for the Management of Hepatitis C Virus Infection Receive CE MarkThe tests detect HCV RNA, which is a crucial marker in the management of hepatitis C infection.
Correction of RT–qPCR Data for Genomic DNA-derived Signals with ValidPrimeHenrik Laurell et al propose a novel method (ValidPrime) that is more accurate than traditional RT(_) controls to test qPCR assays with respect to their sensitivity toward gDNA by compensating for DNA background.
A qPCR-Based Assay to Quantify Oxidized Guanine and Other FPG-Sensitive Base Lesions within Telomeric DNATelomeres are hexamer (TTAGGG) repeats that protect the genome against chromosomal instability and accelerated cellular senescence. This article describes a reliable, cost-effective quantitative PCR (qPCR)-based method to measure the amount of oxidized residues within telomeric DNA that are recognized and excised by formamidopyridine DNA glycosylase (FPG).
Genomic Health Discovers New Gene Networks Associated with Breast CancerStudy provides technical validation of whole transcriptome RNA-Seq as a powerful new tool for clinical research and development. Genomic Health will provide proprietary platform combining whole transcriptome profiling and mutation analysis for large clinical studies.
Roche and Labcyte Integrate Echo and LightCycler Systems to Increase Performance of qPCR-based RNA/DNA AnalysesCompanies cooperate around high-speed, miniaturized quantitative PCR (qPCR) to monitor the expression of tens to thousands of genes for therapeutic research.
Quest Diagnostics Launches Simplexa™ Dengue Test in BrazilCountry's public health labs now evaluating the test's potential for aiding clinical management of the country's nearly one million Dengue fever cases.
Identifying superior reference genes for data normalisation of expression studies via quantitative PCR in hybrid rosesGene expression studies are a prerequisite for understanding the biological function of genes. Because of its high sensitivity and easy use, quantitative PCR (qPCR) has become the gold standard for gene expression quantification.
