Corporate Banner
Satellite Banner
qPCR
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Foundation Medicine’s Next-Generation Sequencing Data to be Presented at 103rd AACR Annual Meeting 2012

Published: Wednesday, March 28, 2012
Last Updated: Wednesday, March 28, 2012
Bookmark and Share
Genomic profile demonstrates high concordance with existing commercial assays and identifies broader range of actionable alterations.

Foundation Medicine, Inc. announced that new data highlighting the company’s next-generation sequencing approach in clinical oncology will be presented at the 103rd American Association for Cancer Research (AACR) Annual Meeting 2012 being held March 31 through April 4 in Chicago.

The presentations will highlight the technical feasibility and clinical relevance of the company’s next-generation sequencing platform for oncology, which offers a fully informative genomic profile of the relevant alterations present in about 200 genes known to be somatically altered in human cancers. In these studies, the profile demonstrated concordance with existing commercial offerings and identified all classes of genomic alterations. In one study being presented, approximately 70 percent of cases were found to carry one or more actionable alterations, meaning the alteration could plausibly confer sensitivity or resistance to approved or experimental targeted therapies. The studies also identified more classes of alterations, including base pair mutations, insertions and deletions, copy number alterations and select gene fusions and rearrangements, than other commercially available molecular diagnostic tests.

“The data presented at AACR show that the breadth and relevance of Foundation Medicine’s genomic profile may offer important information for cancer treatment decisions, while fitting easily into routine clinical practice,” said Vincent Miller, M.D., senior vice president, clinical development, Foundation Medicine. “These findings support the feasibility of our fundamental mission to help practicing oncologists integrate the unique molecular information for each patient’s tumor into clinical decision making.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,600+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
Measuring the Abundance of Extremely Rare Mutations
Researchers from Rutgers University demonstrate the use of multiplex real-time PCR assays to measure the abundance of extremely rare mutations associated with cancer.
Harnessing Helpful Microbes
Seeking to further harness microbes’ many uses, the federal government has launched the National Microbiome Initiative (NMI) to “foster the integrated study of microbiomes across different ecosystems.”
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
New Tool Could Change How Infectious Diseases Are Diagnosed
Scientists at the University of Utah School of Medicine, ARUP Laboratories, and IDbyDNA, Inc., have developed ultra-fast, meta-genomics analysis software called Taxonomer that dramatically improves the accuracy and speed of pathogen detection.
Finding Zika One Paper Disc At A Time
A novel, inexpensive method for detecting the Zika virus could help slow spread of outbreak, and potentially other future pandemic diseases.
Rapid Diagnosis of Bacterial Infections
Mass. General-developed compact system could shorten diagnostic time from days to hours, bring testing to point of care.
Monovar Drills Down Into Cancer Genome
Rice, MD Anderson develop program to ID mutations in single cancer cells.
Biomarkers for Profiling Prostate Cancer Patients
Exiqon A/S has announced the publication of validation of prognostic microRNA biomarkers for the aggressiveness of prostate cancer in independent cohorts.
Gene Analysis System Could Accelerate Pace of Research on the Space Station
The WetLab-2 system will enable spaceflight genomic studies involving a wide variety of biospecimen types in the unique microgravity environment of space.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,600+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!