Corporate Banner
Satellite Banner
qPCR
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

RainDance Launches the Next Generation of PCR

Published: Tuesday, April 03, 2012
Last Updated: Tuesday, April 03, 2012
Bookmark and Share
New RainDrop™ System surpasses all existing digital PCR technologies and establishes new performance standards in cancer research.

RainDance Technologies, Inc. has introduced its new RainDrop™ Digital PCR System, which establishes new performance standards in sensitivity, multiplexing and absolute quantitation in PCR analysis. Capable of generating more than a billion reactions in a single day, the RainDrop System transforms the performance of molecular assays by enabling digital answers across a number of important applications including low-frequency tumor allele detection, gene expression, copy number variation, and SNP measurement. RainDance unveiled the new RainDrop System this week at the annual meeting of the American Association for Cancer Research (AACR) in Chicago.

Built on RainDance’s patented and proven RainStorm™ picodroplet technology, the RainDrop System generates up to 10 million picoliter-sized droplets per lane. Since each droplet encapsulates a single molecule, researchers can quickly determine the absolute number of droplets containing specific target DNA and compare that to the number of droplets with background wild-type DNA. The RainDrop System also shifts the current digital PCR (dPCR) paradigm from a single-color-per-marker approach to a two color and varying probe intensity method that is capable of multiplexing up to 10 markers.(1)
In a recent Lab on a Chip paper,(2) scientists from Université de Strasbourg and Université Paris Descartes, used the RainDance dPCR technology to detect a single mutated copy of KRAS in a background of 200,000 wild-type copies. By processing reactions in millions of picoliter droplets, the platform improved sensitivity by two orders of magnitude compared to existing technologies.

“With RainDance digital PCR, we were able to achieve absolute quantification of mutated and tumor-circulating DNA and improve the detection of a circulating tumor by comparing its proportion to non-tumor DNA,” added Professor Pierre Laurent-Puig, M.D., Ph.D. of the Université Paris Descartes. “Absolute quantification is critical, especially in research that lays the groundwork for future clinical applications, because it allows you to generate meaningful thresholds that will be required for prognostic and diagnostic tools.”

“Two years ago, RainDance embarked on an ambitious goal when it set out to develop a digital PCR technology platform that would fundamentally transform cancer research, and open the door to new ways that cancers may be detected, monitored and treated in the future,” said Roopom Banerjee, President and CEO of RainDance Technologies. “With the introduction of our RainDrop System at AACR, we have realized this vision and officially ushered in the next generation of PCR. As several of our early customers have demonstrated at this meeting, we will soon have absolute answers to many of the most complex questions in cancer research and tumor progression.”

Beginning in the summer of 2012, RainDance will be offering a select number of scientists the opportunity to participate in the RainDrop First Access Program. This multi-day program will consist of both classroom and wet-lab sessions. During the classroom sessions, participants will interact with the senior RainDance scientists responsible for developing this dPCR technology. The wet-lab sessions will provide hands-on instrumentation and software training with assays and samples. Participants will also be able to choose from a fixed menu of assays and run up to 32 of their own samples.

RainDance will be showcasing the new RainDrop System at AACR in booth #2706.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Finding Zika One Paper Disc At A Time
A novel, inexpensive method for detecting the Zika virus could help slow spread of outbreak, and potentially other future pandemic diseases.
Rapid Diagnosis of Bacterial Infections
Mass. General-developed compact system could shorten diagnostic time from days to hours, bring testing to point of care.
Monovar Drills Down Into Cancer Genome
Rice, MD Anderson develop program to ID mutations in single cancer cells.
Biomarkers for Profiling Prostate Cancer Patients
Exiqon A/S has announced the publication of validation of prognostic microRNA biomarkers for the aggressiveness of prostate cancer in independent cohorts.
Gene Analysis System Could Accelerate Pace of Research on the Space Station
The WetLab-2 system will enable spaceflight genomic studies involving a wide variety of biospecimen types in the unique microgravity environment of space.
Liquid Biopsy for NSCLC
'Liquid biopsy' blood test accurately detects key genetic mutations in most common form of lung cancer, study finds.
Rare DNA Will Have Nowhere To Hide
Two National Institutes of Health grants back Rice University effort to develop new diagnostics.
Seeing Cell to Cell Differences
Seeing differences between individual cells for first time explains symptoms of rare genetic disorders, finds penn study.
Circular RNAs Implicated in Cancer
Circular RNAs – like their protein counterparts – are also affected by genomic rearrangements in cancer, resulting in abnormal fusions.
Know Thy Helicobacter pylori
Non-invasive method for genotyping H.pylori developed.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!