Corporate Banner
Satellite Banner
qPCR
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Biosearch Acquires Worldwide Rights to Non-FRET Probes Patents

Published: Thursday, August 23, 2012
Last Updated: Thursday, August 23, 2012
Bookmark and Share
Company has acquired rights from UMDNJ to United States Patent 6,150,097.

Biosearch Technologies, Inc. has announced that the company has acquired worldwide rights from the University of Medicine and Dentistry of New Jersey (UMDNJ) to United States Patent 6,150,097, titled “Nucleic Acid Detection Probes Having Non-FRET Fluorescence Quenching and Kits and Assays Including Such Probes,” as well as counterpart patents in Australia, Canada, France, Germany, Great Britain, Italy, and Japan, that disclose and claim, inter alia, probes having quenchers and fluorophores that are not FRET pairs, as well as their use.

In addition, Biosearch has acquired rights to sublicense the non-FRET probes patents to companies that may wish to commercialize current and future non-FRET probe-based products.

Marc Beal, Director of Corporate Development at Biosearch Technologies, comments, “Biosearch is dedicated to the science and mechanisms of fluorescent quenching along with a daily pursuit for delivering highly multiplexed fluorescent probe solutions. FRET-based probes have a limited and finite mastery of the visible spectrum accessed by the current thermocycler manufacturers and probe suppliers. The UMDNJ non-FRET probe patents will enable Biosearch to design and market new fluorescent quenched probes for quantitative PCR and highly multiplexed fluorescent probe applications. We are very excited to be working with UMDNJ as we again prepare to move the qPCR probe marketplace forward as we did with Black Hole Quencher® (BHQ®) series of dyes in 2000.”

"Although it had been thought that fluorophore-quencher pairs for labeling molecular probes need to interact with each other by fluorescence resonance energy transfer (FRET), a mechanism that restricts the choice of labels to only a few available pairs that interact with each other when separated by a short distance, the non-FRET probes patents licensed by Biosearch show how non-FRET label pairs that interact by forming transient chemical bonds upon contact with each other, enable a wide variety of differently colored fluorophores to be used in combination with many non-fluorescent quenchers (including novel quenchers that are designed to interact in this manner), and the resulting non-FRET probes have found widespread use in multiplex molecular diagnostic assays," says Fred Russell Kramer, co-inventor of non-FRET probes technology.

Vincent Smeraglia, Director of the UMDNJ Office of Technology Transfer & Business Development stated, "The University of Medicine & Dentistry of New Jersey is extremely pleased to expand and bolster our successful ongoing relationship with Biosearch Technologies and announce this new licensing partnership. UMDNJ is confident that Biosearch Technologies, a central player in the probes synthesis market, is the ideal partner to enable adoption of non-FRET probes technology for a wide variety of uses in biomedical applications."


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Biosearch Technologies Licenses RNA FISH-based Inventions from UMDNJ
Stellaris® Probe alliance - NextGen Gene Expression™, SNP FISH™, and iceFISH™ in research and clinical applications.
Tuesday, March 19, 2013
Biosearch Appoints Uniscience as Brazilian Distributor
Uniscience to sell, market, and support Biosearch’s inventoried and custom products in the country of Brazil.
Tuesday, May 22, 2012
Biosearch and Seegene Finalize Oligonucleotide Supply and BHQ®, CAL Fluor® and Quasar® Licensing Agreements
Biosearch will manufacture both research and IVD grade oligonucleotides for Seegene.
Thursday, October 21, 2010
Biosearch Technologies Awarded Second Phase II Army SBIR Grant
The $750,000+ Phase II grant will continue the design and development of accurate assays for pathogens of military importance.
Thursday, October 14, 2010
Biosearch Technologies Awarded Phase II Army SBIR Grant
The $800,000+ Phase II grant is aimed to back the design and development of rapid and accurate assays for pathogens of military importance.
Thursday, September 23, 2010
Biosearch Technologies Expands Licensing of QIAGEN Scorpions®
According to the agreement, the company obtains rights to manufacture primer assays for research, applied markets and infectious diseases.
Friday, August 13, 2010
Biosearch Technologies Selected for SBIR Grants Issued by the DoD for Disease Detection
Both the Phase I grants aim to develop sensitive analyte specific reagents for a total of twelve pathogens of military importance.
Friday, October 09, 2009
Biosearch Technologies Provides Probe and Primer Reagents for Swine Influenza A/H1n1 Viral Strains
The Company responds to the swine influenza pandemic by offering the rapid custom synthesis of all research use only oligonucleotide probes and primers.
Monday, May 18, 2009
CAL FluorR Patent Issued to Biosearch Technologies
Company has been awarded U.S. Patent describing the CAL Fluor® series of fluorescent dyes for modifying synthetic DNA to enhance its detectability.
Wednesday, April 02, 2008
Scientific News
RNAi Screening Trends
Understand current trends and learn which application areas are expected to gain in popularity over the next few years.
Diagnostic Test Developed for Enterovirus D68
researchers at Washington University School of Medicine in St. Louis have developed a diagnostic test to quickly detect enterovirus D68 (EV-D68), a respiratory virus that caused unusually severe illness in children last year.
Simple Technology Makes CRISPR Gene Editing Cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA.
HPV Genomes Show Greater Diversity Than Expected in Cancer Patients
The findings could have implications for eventually understanding why some cervical lesions become malignant.
Rapidly Detecting Drug-Resistant HepC
A nested PCR-based assay has been shown to rapidly and accurately detect drug-resistant strains of the hepatitis C virus.
Researchers Seek Water Test for Invasive Species Detection
Detecting invasive lake and river species using just a water sample would be a dream come true for wildlife managers and regulators in the state and University of Maine researchers may soon make this an inexpensive reality.
New Cell Structure Finding Might Lead to Novel Cancer Therapies
University of Warwick scientists in the U.K. say they have discovered a cell structure which could help researchers understand why some cancers develop.
Ebola Assays Compared in Head-to-Head Analysis
A newly published study has attempted to rigorously evaluate a few of the assays recently granted Emergency Use Authorization by the US Food and Drug Administration to test for Ebola Zaire virus.
Profiling DNA Viruses in Arctic Lakes
The Arctic's freshwater lakes contain viral communities composed of DNA viruses from lineages that are largely distinct from those described elsewhere, a new study suggests.
Polar Distribution of MicroRNAs Discovered within Eukaryotic Cells
A plausible new mechanism contributing to asymmetric cell division.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!