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Webcasts
Drug Sensitivity and Resistance Testing Platform for Personalized Medicine at the Institute for Molecular Medicine Finland (FIMM)
Jani Saarela, Institute for Molecular Medicine, speaking at Screening Europe 2015
Evolution and Selection of Soybean Nematode Resistance Locus
Tong Geon Lee, University of Illinois at Urbana Champaign, speaking at Advances in Plant Genomics 2014

Market Reports
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Biomarkers in Late-Stage Clinical Trials: Applications, opportunities and activities of leading players
Business Insights

Biomarkers reduce the attrition rate of late-stage clinical trials by assessing drug potential in terms of efficacy and toxicity at the early stages of clinical development. Thus, biomarkers significantly increase productivity, lower the cost and duration of clinical trials, and help researchers complete the drug development process at a faster pace.
Epigenetics Market Trends 2011
Select Biosciences Ltd

Epigenetics research efforts are growing around the world driven by the numerous documented associations of epigenetic modifications with diseases—especially various types of cancers.
Multiplexed Diagnostics 2010
Select Biosciences Ltd

The multiplexed diagnostics market has grown rapidly and generated sales of approximately $2.4 billon in 2009, but is now balanced on multiple tipping points.
Scientific News
New Method Promises to Speed Development of Food Crops
A new study addresses a central challenge of transgenic plant development: how to reliably evaluate whether genetic material has been successfully introduced.
Study Validates Analysis of Copy Number Variation in Miniaturized Reaction Volumes
Data shows that accurate and reproducible CNV results can be produced with IntelliQube using the Array Tape® consumable.
Faster Drug Discovery?
Startup develops more cost-effective test for assessing how cells respond to chemicals.
Edited Stem Cells Offer Hope of Precision Therapy for Blindness
Findings raise the possibility of treating blinding eye diseases using a patient's own corrected cells as replacement tissue.
Parallel Single-Cell Profiling
New single-cell genomics protocol allows researchers to study links between DNA modifications (methylation) and the activity of a gene.
Pathogens Found in Iceman's Gut
Scientists discover Helicobacter pylori in the contents of Ötzi’s stomach along with some unexpected insights into the coexistence of man and bacterium.
Diagnosing Cancer from a Single Drop of Blood
What if a physician could effectively diagnose cancer from one drop of a patient’s blood?
Tracing a Cellular Family Tree
New technique allows tracking of gene expression over generations of cells as they specialize.
Accelerating Protein Evolution
A new tool enables researchers to test millions of mutated proteins in a matter of hours or days, speeding the search for new medicines, industrial enzymes and biosensors.
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
Business News
TATAA Biocenter Announce Strategic Partnership with Yikon Genomics
TATAA Biocenter and Yikon Genomics has Announced Strategic Partnership to distribute Yikon’s MALBACTM products for single cell profiling and YK-PGSTM Solutions in Europe.
Swift Biosciences, SeraCare Partner
Swift Biosciences and SeraCare Life Sciences have announced a partnership to accelerate development of a novel circulating tumor DNA reference material.
Douglas Scientific, TATAA Biocenter Collaborate
Both Companies launch new high throughput PCR services.
Thermo Fisher Scientific to Acquire Affymetrix
Strengthens leadership in biosciences and genetic analysis.
Applied Maths Joins the bioMérieux Family
bioMérieux, a world leader in the field of in vitro diagnostics, today announced the acquisition of Applied Maths, a company that develops state-of-the-art software solutions for the biosciences, in particular for databasing, analysis and interpretation of complex biological data.
Transgenomic Awarded NIH Grant
STTR grant supports addition of greater multiplexing capabilities to ICE COLD-PCR, an advanced technology that enables use of tissue or liquid biopsy samples and provides up to 500-fold increase in mutation detection on any sequencing platform.
InstantLabs Launches Two Additional Salmon ID Tests
New species ID tools bolster growing product line from manufacturer of the Hunter® testing system.
Immunexpress Releases Key Performance Data on SeptiCyte®
Immunexpress, Inc., a molecular diagnostic company committed to improving outcomes for suspected sepsis patients, have announced the publication of the discovery and validation of the SeptiCyte® Lab test for sepsis.
Novel qPCR-based PrenaTest® Successfully Validated in Clinical Study
LifeCodexx AG’s cost-efficient NIPT assay to provide results on fetal trisomy 21 in 48 hours.
Epic Sciences, Abramson Cancer Center Partner
Epic Sciences has announced a collaboration with the Abramson Cancer Center of the University of Pennsylvania (Penn) on multiple studies to explore biomarkers, identified by analysis of circulating tumor cells (CTCs) at a single cell resolution, that are predictive of response to personalized cancer therapeutics.

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06 Mar 2016
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Single Molecule & Single Cell
15 Mar 2016
Single Molecule & Single Cell ...
Lab-on-a-Chip Europe & Microfl
15 Mar 2016
Lab-on-a-Chip Europe & Microfl ...

ePosters
Single Cell Whole Genome Amplification
GE Global Research

The analysis of genomes at the single cell level offers unprecedented biological insights in diverse fields such as cancer research, immunology & microbiology. This poster discusses the a technology for amplification of genomic DNA form a single cell, that provides utmost sensitivity, accuracy & robustness. GE Healthcare Life Sciences had previously developed method of multiple strand displacement amplification (MDA) by Phi29 DNA polymerase
System-Specific Periodicity in qPCR Data and its Impact on Quantitation
1Dept. of Chemistry, Vanderbilt Univ., Nashville, TN USA 37235; 2 BTU Cottbus-Senftenberg, Senftenberg, Germany; 3 Dept. of Andrology, Univ. Hospital Hamburg-Eppendorf, Germany

In some commercial qPCR instruments, the fluorescence signal shows reaction-to-reaction periodicity in all cycles, and this translates into periodicity in threshold-based Cq markers.
A Microwave/Microfluidics Integrated Label-Free Detection and Content Sensing System for Point-of-Care Applications
University of Waterloo

This poster presents a droplet-based microfluidic device integrated with a microwave wave sensor, which is also a heater, for simultaneous sensing and heating of individual nanoliter-sized droplets.
Rapid Detection of Somatic Mutations in Cancer Genes
DiaCarta, Inc.

Rapid higly sensitive detection of tumor gene mutations in DNA derived from FFPE or plasma samples can be achieved with QClamp PCR technology.
Accurate Normalization of Grain Samples Using Pressure-Based Volume Measurement Technology
Artel and STRATEC

A common challenge experienced by sample screening facilities is identifying individual sample quantity prior to DNA extraction. Accurately identifying sample quantity allows the user to pipette exact amounts of extraction buffer into each well.
DHPLC Technology as a High-throughput Detection of Mutations in a Durum Wheat TILLING Population
1Department of Soil, Plant and Food Sciences, sect. Genetics and Plant Breeding, University of Bari, Via Amendola 165/A, 70126 Bari (Italy) 2 Transgenomics Omaha, NE, USA

This study is a beautiful example of DHPLC technology application and shows an alternative tool to current strategies of SNP detection based on genotyping array.
IDENTIFICATION AND DIFERENTIATION OF Verticillium SPECIES WITH PCR MARKERS AND SEQUENCING OF ITS REGION


The genus Verticillium is a group of ascomycete fungi, including plant-pathogenic species capable of affecting the vasculature of many agricultural crops, and therefore causes major economic losses worldwide. In 2011, a new taxonomic classification of the genus was proposed, which is now referred to as Verticillium sensu stricto, comprising ten species: V. dahliae V. albo-atru, V. alfalfae, V. longisporum, V. nonalfalfae, V. tricorpus, V. zaregamsianum, V. nubilum, V. isaacii and V. klebahnii. <
Expression Profiling of Circulating Tumor Cells: a Prognostic and Predictive Biomarker in Cancer.
Bauer4.1TATAA Biocenter, Göteborg, Sweden (www.tataa.com); 2Inst. of Biotechnology, CAS, Czech Republic; 3AdnaGen GmbH, Ostpassage7, D-30853 Langenhagen, Germany (www.adnagen.com); 4Dep of Gynecoland

We show non-responders to treatment among breast cancer patients can be identified by expression profiling of circulating tumor cells
Detection in Environmental Samples of Enteroagregative Escherichia coli, stx-producing Escherichia coli and stx-converting Bacteriophage by RT- PCR: Preliminary Data
Istituto Zooprofilattico Sperimentale della Sardegna- Italy

The aim of this work was to collect epidemiological information concerning the presence of Enteroaggregative Escherichia coli, stx-producing Escherichia coli and stx2a-converting bacteriophage, in ruminants faeces.
Effect of exposure to stress conditions on propidium monoazide (PMA) - qPCR based enumeration of Campylobacter in broiler carcass rinses
1 Laboratory of Food Microbiology and Food Preservation, Dept Food Safety & Food Quality Faculty of Bioscience Engineering, Gent, Belgium 2 Institute of Public Health, Scientific service Food-borne pa

Evaluation and comparison of a developed PMA-qPCR Campylobacter enumeration method with the reference method, after exposure of the broiler rinse artificially contaminated with the bacteria to stress conditions.
Application Notes
Directional qRNA-Seq: Combining the Power of Stranded RNA-Seq with the Quantitative Precision of Molecular Labels
Bioo Scientific

Bioo Scientific introduces a novel product for advanced RNA-Seq library preparation that features strand-specific RNA sequencing and correction of PCR amplification bias by molecular indexing: the NEXTflex™ Rapid Directional qRNA-Seq™ Kit.
Double stranded DNA quantitation using Promega QuantiFluor® Dyes
Tecan Group Ltd.

Achieving selective and sensitive quantitation of double stranded DNA (dsDNA) using spectrophotometric methods can be problematic. Recognizing these difficulties, researchers have incorporated fluorescence-based quantitation techniques in their workflows to obtain the required sensitivity and target selectivity.
Rapid, High Throughput Extraction and Purification of Genomic DNA from Whole Blood Using the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling System
Hamilton

This application note demonstrates the high precision of the automated extraction system in processing genomic DNA from low volume whole blood samples and its advantage over competitors.
Automated GS FLX Titanium emPCR Enrichment using the REM e System on a Hamilton Microlab® STARlet Liquid Handler
Hamilton

The Genome Sequencer FLX System is a versatile sequencing platform suitable for a wide range of research applications, including de novo sequencing and assembly of genomic DNA, transcriptome sequencing, small RNA analysis, and amplicon sequencing.
A MIQE Case Study — Effect of RNA Sample Quality and Reference Gene Stability on Gene Expression Data
Bio-Rad Laboratories

In this study, the minichromosome maintenance (MCM) protein, MCM7, was selected as a model target gene to investigate the importance of appropriate reference gene selection and RNA sample quality as described by the MIQE guidelines.
Sequence-Specific DNA Assay
Molecular Devices

The Threshold® system from Molecular Devices, together with the Immuno Ligand Assay (ILA) kit can be used to measure specific DNA sequences. Biotinylated or fluorescienated oligonucleotide probes, specific to the target sequence, anneal to the digested target DNA creating a probe-target hybrid which can then be detected and quantified against a standard curve, with pleasing results.
High Yield and Quality with Thermo Scientific Microtiter Deep Well 96 plates in KingFisher Flex Process
Thermo Fisher Scientific

The Thermo Scientific KingFisher Flex magnetic particle processor is specifically designed to automate the time-consuming sample preparation of proteins, nucleic acids and cells in 96-well plate formats.
Isolation and Purification of Genomic DNA and Viral RNA from Clinical Samples with Thermo Scientific KingFisher Flex
Thermo Fisher Scientific

The purification of DNA and RNA from clinical samples requires rapid and reliable processing of large quantities of samples. Automated purification of nucleic acids, proteins and cells with Thermo Scientific KingFisher Flex is a reproducible and high quality method, which produces excellent material for further analyses.
Efficient Delivery of Thermo Scientific Dharmacon SMARTpool siRNA Reagents in Difficult-to-Transfect Cell Lines Using Nucleofector® 96-well Shuttle® System
Lonza

siRNA-mediated gene knockdown is a powerful tool that has been used to identify gene function and elucidate biological pathways. Successful siRNA experiments involving knockdown of individual genes or collections of gene targets require efficient delivery of highly functional and specific siRNA molecules into appropriate cells.
ScreenTape® Enables Fast Quality Control of miRNA qPCR Reactions
AnaSpec

The ScreenTape® System, developed by Lab901, employs a unique microscale polymer tape that contains all the reagents required for DNA electrophoresis. It brings major advantages of convenience, ease of use and safety to molecular biologists as absolutely no handling of gels and buffers is required.
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