Comparison of Microfluidic Digital PCR and Conventional Quantitative PCR for Measuring Copy Number Variation
Published: Thursday, March 08, 2012 Last Updated: Thursday, March 08, 2012
This study uses an in vitro BC gene amplification model to identify when a CNV is too small to be measured by qPCR and dPCR. Subsequently, we developed a model, based on the Poisson and binomial distributions, to determine the variance inherent in dPCR.
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