Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>Resources>Application Notes>This Application Note
  Application Notes
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
New Analysis Technique for Chiral Activity in Molecules
Professor Hyunwoo Kim of the Chemistry Department and his research team have developed a technique that can easily analyze the optical activity of charged compounds by using nuclear magnetic resonance (NMR) spectroscopy.
Measuring microRNAs in Blood to Speed Cancer Detection
A simple, ultrasensitive microRNA sensor holds promise for the design of new diagnostic strategies and, potentially, for the prognosis and treatment of pancreatic and other cancers.
Best Test to Diagnose Strangles in Horses Identified
New research by Dr. Ashley Boyle of New Bolton Center’s Equine Field Service team shows that the best method for diagnosing Strangles in horses is to take samples from a horse’s guttural pouch and analyze them using a loop-mediated amplification (LAMP) polymerase chain reaction (PCR) test.
Tardigrade's Are DNA Master Thieves
Tardigrades, nearly microscopic animals that can survive the harshest of environments, including outer space, hold the record for the animal that has the most foreign DNA.
Lucentis Effective for Proliferative Diabetic Retinopathy
NIH-funded clinical trial marks first major advance in therapy in 40 years.
Antibiotics on Our Plates 'Could Lead to Health Catastrophe'
Two medical experts from The University of Queensland are urging China to curb its use of antibiotics in animals to avoid what could be a ‘major health catastrophe’ for humans.
The Secret Behind the Power of Bacterial Sex
Migration between different communities of bacteria is the key to the type of gene transfer that can lead to the spread of traits such as antibiotic resistance, according to researchers at Oxford University.
Farming’s in Their DNA
Ancient genomes reveal natural selection in action.
Personalized Drug Screening for Multiple Myeloma Patients
A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer.
Scroll Up
Scroll Down

Fully Automated 24-Well Madin-Darby Canine Kidney (MDCK) Permeability Assay Utilizing the Hamilton Microlab® Star Liquid Handling Platform
Bookmark and Share


Permeability assays are used to elucidate the structure-activity relationships in the hit-to-lead stage, rank order compounds for in vivo pharmacokinetics studies, and predict the potential for oral absorption. It is important to have reliability, accuracy and precision for such assays especially when used in mid-high throughput screening. This application note describes the fully automated 24-well Madin-Darby Canine Kidney (MDCK) permeability assay using the MICROLAB STAR liquid handling workstation.

Further Information

Related Content

Hamilton Storage Technologies Opens 52,000-Square-Foot Facility in Franklin, Massachusetts
Innovative open floor plan helps life science business address growing market demands.
Tuesday, January 22, 2013
Hamilton Robotics and French Police Scientifique Publish Paper Describing Large-Scale Production of Genetic Profiles
More than 300,000 profiles have already been processed on the Hamilton platforms and stored in French Database.
Wednesday, March 10, 2010
Hamilton Star Liquid Handler Installation at the Diamond Light Source MPL Laboratory
Hamilton Robotics has installed a STAR liquid handler at the commissioned Membrane Protein Crystallography Laboratory at the Diamond Light Source near Didcot in Oxfordshire.
Monday, June 11, 2007
Automation of Adherent Cell Culture Maintenance
Hamilton, Life & Brain and University of Bonn will jointly develop a system for the automated culture of primary cells, cell lines and embryonic stem cells.
Monday, May 14, 2007
Introduction of an Anti Droplet Control Pipette
HAMILTON introduces ADC, for pipetting volatile organic solvents, with pressure sensors in the pipetting channel to monitor each pipetting step.
Monday, December 11, 2006
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos