Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>Resources>Application Notes>This Application Note
  Application Notes
Scientific News
Benchtop Automation Trends
Gain a better understanding of current interest in and future deployment of benchtop automated systems.
The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Study Identifies How Brain Connects Memories Across Time
UCLA Neuroscientists have boost ability of aging brain to recapture links between related memories.
3-D Atomic Structure of Cholesterol Transporter
Researchers at UTSW have determined the 3-D atomic structure of a human sterol transporter that helps maintain cholesterol balance.
First Large-Scale Proteogenomic Study of Breast Cancer
The study offers understanding of potential therapeutic targets.
Can We Break the Link Between Obesity and Diabetes?
Columbia University researchers identify a key molecule involved in the development of type 2 diabetes.
Fungi – A Promising Source Of Chemical Diversity
Moulds and plants share similar ways in alkaloid biosynthesis .
How Prions Kill Neurons: New Culture System Shows Early Toxicity to Dendritic Spines
Boston University researchers have developed a cell culture system to study prions.
Great Migration and African-American genomic diversity
Study examines genetic data to analyze regional differences in ancestry.
Faster, More Efficient CRISPR Editing
UC Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool.
Scroll Up
Scroll Down

A Novel Method for the Extraction of Mitochondrial DNA from Human Hair, Skin, and Blood Stain
Bookmark and Share


Pressure Biosciences Inc.

Forensic samples are often limited in their quantity; in addition, the quality of their biomolecules may also be in relatively poor condition. If there is insufficient material for nuclear DNA analysis, mitochondrial DNA (mtDNA) can provide great sensitivity and valuable information from samples such as hair, skin, or blood stains, by taking advantage of the fact that cells may contain thousands of copies mtDNA, while somatic cells typically contain two copies of nuclear DNA. In an effort to increase the safety, speed, simplicity, and efficiency of mtDNA extraction from forensic specimens, Pressure BioSciences, Inc. (PBI) has developed a novel extraction system based on a new, patented process called Pressure Cycling Technology (PCT). This PCT Sample Preparation System (PCT SPS) eliminates the requirement for the use of harsh chemicals and time consuming processes to extract and purify mtDNA from a number of samples. Furthermore, mtDNA may be released from the specimen in the single-use container in which the sample was collected, transported, and stored (PULSE Tube). In addition, mtDNA released by PCT from hair, skin, or blood can be amplified directly by PCR without the need for additional purification. Consequently, the PCT SPS offers a safer, more rapid, simpler, and more efficient method for extracting mtDNA.

Further Information


Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!