Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>Resources>Application Notes>This Application Note
  Application Notes
Scientific News
Fixing Holes in the Heart Without Invasive Surgery
UV-light enabled catheter is a medical device which represents a major shift in how cardiac defects are repaired.
Chromosomal Chaos
Penn study forms basis for future precision medicine approaches for Sezary syndrome
Enzyme Malfunction May be Why Binge Drinking Can Lead to Alcoholism
A new study in mice shows that restoring the synthesis of a key brain chemical tied to inhibiting addictive behavior may help prevent alcohol cravings following binge drinking.
Key to Natural Detoxifier’s Reactivity Discovered
Results have implications for health, drug design and chemical synthesis.
New Treatment for Obesity Developed
Researchers at the University of Liverpool, working with a global healthcare company, have helped develop a new treatment for obesity.
New Protein Found in Immune Cells
Immunobiologists from the University of Freiburg discover Kidins220/ARMS in B cells and demonstrate its functions.
Will Brain Palpation Soon Be Possible?
Researchers have developed non-invasive brain imaging technique which provides the same information as physical palpation.
Shaking Up the Foundations of Epigenetics
Researchers at the Centre for Genomic Regulation (CRG) and the University of Barcelona (UB) published a study that challenges some of the current beliefs about epigenetics.
Groundbreaking Computer Program Diagnoses Cancer in Two Days
Researchers have combined genetics with computer science and created a new diagnostic technology can with 85 per cent certainty identify the source of the disease and thus target treatment and, ultimately, improve the prognosis for the patient.
Michigan Researchers Use Raman Spectroscopy
inVia confocal Raman microscope used in the study of various childhood diseases.
Scroll Up
Scroll Down

Tag-lite® two-cell assay: a valuable tool for protein drug discovery
Bookmark and Share

Tecan Group Ltd.

The Tag-lite technology, developed by Cisbio Bioassays, is a combination of a classical TR-FRET and SNAP-tag® technology (New England Biolabs), which allows antigens present on the cell surface to be labelled with a fluorescent donor or acceptor dye. 

The assay involves the generation of two labelled cell populations; one cell type with terbium (donor fluorophor) labelled human FcγRIIIa, and a second with surface displayed antigen Y labelled with SNAPRed (acceptor fluorophor). In the presence of an antibody which can bind both labelled proteins, the cells will come into close enough proximity to allow energy transfer between fluorophores. 

The combination of this assay system with the excellent sensitivity and flexible wavelength and bandwidth selection offered by the Infinite® M1000 PRO multimode reader provides an invaluable tool for the assay development process. This will allow more in-depth analysis of protein-protein interactions in a physiologically relevant, cell-based environment.

Further Information

Related Content

Tecan Academy Launched in Europe
An online training tool that makes it easier for customers to optimize their instrument use.
Wednesday, October 09, 2013
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos