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Determination of Sulfonamide Antibiotics in Wastewater by LC / MS
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Thermo Fisher Scientific

Sulfonamides are a common class of synthetic antimicrobials that are widely used in human and veterinary medicine and also as additives in animal feed. They are regarded as emerging environmental contaminants (water, sediment, soil). There are no definitive regulations for LODs of these compounds in the environment, due to lack of knowledge of the fate of such pharmaceutical compounds in waste water. Therefore, sensitive and reliable analytical methods for detection of sulfonamides are needed by environmental laboratories.

Attached is a new application note from a key environmental laboratory in Europe (The General Chemical State Laboratory, Athens, Greece), for monitoring the following sulfonamides in secondary effluent collected from sewage treatment plants :

All analytical work was carried out on a Quantum Ultra. Detection limits ranged in the low ppt levels, with excellent linearity between 0.1 to 100 ug/L (r2 0.997-0.999)

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