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Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
New Imaging Technique in Alzheimer’s Disease
Study confirms new imaging technique corresponds a higher degree of actual brain changes.
ReadCoor Launched to Commercialize 3D Sequencing Tech
ReadCoor will leverage the Wyss Institute’s method for simultaneously sequencing and mapping RNAs within cells and tissues to advance development of diagnostics.
NCI Collaborates with Multiple Myeloma Research Foundation
NCI collaborates with MMRF to incorporate genomic and clinical data into NCI Genomic Data Commons database.
Ancient Eggshell Protein Breaks Through DNA Time Barrier
Fossil proteins from a 3.8million year-old eggshell have been identifed, suggests proteins could give insight into evolutionary tree.
Anti-Inflammatory Drugs Could Strengthen Airway Immunity
Mold toxins can weaken the airways' clearing mechanisms and immunity, but PKC inhibitors showed promise as a treatment.
Monkeys Protected by Zika DNA Vaccine
Experimental Zika virus DNA vaccines successfully protected monkeys against Zika infection.
Probe Identifies Schizophrenia Genes That Stunt Brain Development
Scientists have isolated schizophrenia-related gene variants that change gene expression in the brain.
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Novel ProteoPrep® 20 Immunoaffinity Depletion Resin for Human Plasma
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Sigma Aldrich

The study of the human plasma proteome is an area of hugeimportance, especially for the pharmaceutical potential ofidentifying disease biomarkers. Many proteins of interestappear at low concentrations in the plasma and are, therefore,difficult to detect.

Identification of potential biomarkers is especially difficult dueto the presence of higher abundance proteins. To addressthese issues, an affinity resin has been developed for removalof 20 high abundance proteins from 8 µl of plasma. Depletionof these abundant proteins allows for visualization of proteinsthat co-migrate with, and are masked by, the high abundanceproteins during 1-D or 2-D gel electrophoresis andHPLC separations. Plasma proteins can then be loaded ontogels, IPG strips, or HPLC columns at higher levels for improvedvisualization/detection of low copy number proteins.

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