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Accelerating Spirocyclic Polyketide Synthesis
Powerful flow chemistry techniques used for complex multi-stage synthesis of spirocyclic polyketides.
MS Drug Candidate Shows Promise for Ulcerative Colitis
Positive new clinical data were released today on a drug candidate for ulcerative colitis that was first discovered and synthesized at The Scripps Research Institute.
First Atlas of Body Clock Gene Expression in Mammals Informs Timing of Drug Delivery
Penn Medicine study has implications for 100 top-selling US drugs, half of which target daily-oscillating genes.
New Technique has Profound Implications for Drug Development
The method, developed by Scripps Research Institute chemists, expands options for making pure batches of ‘one-handed’ molecules.
Blood Test Developed to Diagnose Early Onset Alzheimer’s Disease
New blood-test could predict a person’s risk of developing AD much earlier than is currently possible.
Tea and Citrus Products Could Lower Ovarian Cancer Risk
New UEA research finds that women who consume foods containing flavonols and flavanones significantly decrease their risk of developing epithelial ovarian cancer.
TxCell Achieves Positive Results for Col-Treg in a Model of Autoimmune Uveitis
TxCell set for phase I/II proof of principle clinical study in Q2 2015 for its second therapeutic candidate in this rare eye disease.
Heart Drug May Help Treat ALS, Mouse Study Shows
Scientists blocked the enzyme in ALS astrocytes using digoxin, a medication used in the treatment of heart failure.
Team Discovers How Microbes Build a Powerful Antibiotic
Researchers discovery opens up new avenues of research into thousands of similar molecules.
LLNL, UC Davis Partner to Personalize Cancer Medications
With a $7.8 million, five-year grant from the NIH researchers are utilizing accelerator mass spectrometry for cancer research.
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Centrifuge-on-a-Chip and Next-Generation Integrated Microfluidics
A microfluidic chip that can mimic the functions of a centrifuge without moving parts or external forces has been designed by Dino Di Carlo and colleagues from the University of California, Los Angeles.
Wednesday, August 17, 2011
Aminoazines and their Affinity for Graphite
In this CrystEngComm Hot article James D. Wuest and co-workers from the University of Montréal, Canada, look at crystalline amino-substituted azines.
Monday, June 27, 2011
Exciting New Leads in the Fight against Malaria
Researchers from the University of Liverpool and the London and Liverpool Schools of Tropical Medicine have developed a new series of tetraoxane analogues and screened them for their in vitro and in vivo antimalarial activity.
Monday, June 27, 2011
Strategies in Organocatalysts Immobilisation
This review summarizes the successful application of non-covalent interactions, such as acid–base interaction, ion–pair interaction, hydrophobic interaction and so on, in assembling recoverable and reusable organocatalysts.
Friday, June 17, 2011
Nanorods Make a Stand
Utilizing an interesting seed-mediated approach ZnO nanorods were helped to “stand” vertically on microsubstrates.
Monday, June 13, 2011
Drugs that go beyond the rule of five – or do they?
In this HOT paper, published in MedChemComm, researchers from Pfizer explore the influence of intramolecular hydrogen bonding on the membrane permeability and bioavailability of these drugs.
Friday, June 03, 2011
The Importance of Green Chemistry in Process Research and Development
Concern for our planet and its well being is forcing chemists to think about greener, more sustainable processes to make the things we need and want, such as new technologies, fuels and drugs.
Wednesday, June 01, 2011
Assembling Isoniazid
This paper, published in the journal CrystEngComm, describes how researchers have modified the hydrogen bonding in isonicotinic acid hydrazide (isoniazid) in order to control the self-assembly process.
Monday, May 23, 2011
RSC Holds 5th Conference on High Throughput Medicinal Chemistry
The conference will explore technology-enabled drug discovery and new synthetic technologies, focusing medicinal chemistry on 12th May 2009 in Cheshire, UK.
Monday, May 04, 2009
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