Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>Resources>White Papers>This White Paper
  White Papers
Scientific News
Atriva Therapeutics GmbH Develops Innovative Flu Drug
Highly effective against seasonal and pandemic influenza.
New Gene Therapy for Vision Loss From a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Study Removes Cancer Doubt for Multiple Sclerosis Drug
Researchers from Queen Mary University of London are calling on the medical community to reconsider developing a known drug to treat people with relapsing Multiple sclerosis after new evidence shows it does not increase the risk of cancer as previously thought.
Self-Propelled Powder to Stop Bleeding
UBC researchers have created the first self-propelled particles capable of delivering coagulants against the flow of blood to treat severe bleeding, a potentially huge advancement in trauma care.
Five New Genetic Variants Linked to Brain Cancer Identified
The biggest ever study of DNA from people with glioma – the most common form of brain cancer – has discovered five new genetic variants associated with the disease.
Antibody Treatment Efficacious in Psoriasis
An experimental, biologic treatment, brodalumab, achieved 100 percent reduction in psoriasis symptoms in twice as many patients as a second, commonly used treatment, according to the results of a multicenter clinical trial led by Mount Sinai researchers.
Predictive Model for Breast Cancer Progression
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
Probing the Forces Involved in Creating The Mitotic Spindle
Scientists at The Rockefeller University reveal new insights into the mechanical forces that govern elements of the mitotic spindle formation.
Identifying Cancer’s Food Sensors May Help to Halt Tumour Growth
Oxford University researchers have identified a protein used by tumours to help them detect food supplies. Initial studies show that targeting the protein could restrict cancerous cells’ ability to grow.
Fatty Liver Disease and Scarring Have Strong Genetic Component
Researchers say that hepatic fibrosis, which involves scarring of the liver that can result in dysfunction and, in severe cases, cirrhosis and cancer, may be as much a consequence of genetics as environmental factors.
Scroll Up
Scroll Down

Laser Capture Microdissection and Microarray Profiling of Postnatal Brain Development in Rhesus Macaque
Bookmark and Share

NIH Blueprint

Non-human primates provide experimentally tractable model systems that allow carefully controlled analysis of important developmental processes relevant for human health and disease. The goal of the NIH Blueprint Non-Human Primate (NHP) Atlas is to provide a detailed analysis of gene expression in the normal developing primate brain from birth through adulthood in brain regions associated with high-level cognitive, mnemonic and emotional functions as well as neurodevelopmental disorders linked to disruption of these capacities.

A major component of the NHP atlas is genome-wide transcriptional profiling aimed at the identification of transcriptional programs differentially active at different stages of brain maturation in neonates, infants, juveniles and adults. The second phase of this profiling consists of microarray profiling of finely dissected tissue samples from subdivisions of the medial prefrontal cortex, primary visual cortex, hippocampus, amygdala and ventral striatum. Each subdivision is profiled in three independent biological replicate specimens at each of four postnatal developmental stages (0, 3, 12 and 48 months) using Affymetrix GeneChip Rhesus Macaque Genome Arrays.

This document describes details about the generation of these microarray data, which are freely accessible for download.

Further Information

Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos