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Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Apricot Kernels Pose Risk of Cyanide Poisoning
Eating more than three small raw apricot kernels, or less than half of one large kernel, in a serving can exceed safe levels. Toddlers consuming even one small apricot kernel risk being over the safe level.
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Understanding Female HIV Transmission
Glowing virus maps points of entry through entire female reproductive tract for first time.
Genetic Markers Influence Addiction
Differences in vulnerability to cocaine addiction and relapse linked to both inherited traits and epigenetics, U-M researchers find.
Lab-on-a-Chip for Detecting Glucose
By integrating microfluidic chips with fiber optic biosensors, researchers in China are creating ultrasensitive lab-on-a-chip devices to detect glucose levels.
A lncRNA Regulates Repair of DNA Breaks in Breast Cancer Cells
Findings give "new insight" into biology of tough-to-treat breast cancer.
COPD Linked to Increased Bacterial Invasion
Persistent inflammation in COPD may result from a defect in the immune system that allows airway bacteria to invade deeper into the lung.
Detection of HPV in First-Void Urine
Similar sensitivity of HPV test on first void urine sample compared to cervical smear.
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Bioinformatics and the Future of Medicinal Research and Clinical Practice
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DVC, LLC

The enormous advances in biological technology over the past four decades have led to a profound change in how information is processed; conceptual and technical developments in experimental and molecular biology disciplines such as genomics, transcriptomics, proteomics, metabolomics, immunomics, and countless other “omics” have resulted in a veritable sea of data with the potential to radically alter biomedicine. Yet, with this wealth of data comes a challenge, namely how to transform the data into information, the information into knowledge, and the knowledge into useful action.

Nearly coincident with the advances in biological science, and in fact rapidly outpacing such advances, has been the advent of the modern computer and the associated advances in information storage, retrieval, and processing made practical with microelectronics and informatics. The power of modern information technology is ideal for capturing and storing the huge volume of biological data being generated; however, the respective languages and concepts of biology and computer sciences have, until recently, been disparate enough to prevent the logical next step of combining the two disciplines into a more powerful tool. The discipline of bioinformatics has emerged to capture the information stored in living systems and help turn it into actionable technology. In this paper we will explore the precepts of this discipline, the tools, and the potential for the future inherent in this powerful meta-technology.

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