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Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care or “bedside” diagnostics.
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
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One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
Blood Pressure Drug May Boost Effectiveness of Lung Cancer Treatment
Researchers at Imperial College London have suggested that the blood pressure drug may make a type of lung cancer treatment more effective.
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New Discovery May Benefit Farmers Worldwide
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Antibodies Paving the Way to HIV Vaccine
Researchers uncover factors responsible for the formation of broadly neutralizing HIV antibodies in humans.
Designing Drugs with a Whole New Toolbox
Researchers develop methods to design small, targeted proteins with shapes not found in nature.
Protein Studies Discover Molecular Secrets
Two protein studies have mapped proteins that reveal the secrets to recycling carbon and healing cells.
Tapping Evolution to Improve Biotech Products
Researchers show how 'ancestral sequence reconstruction' can be used to guide engineering of a blood clotting protein.
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Next-Generation Data Storage
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Quantum Corp.

The explosion in life sciences data in general, and next-generation sequencing in particular, is nothing short of remarkable. At the 2010 Bio-IT World Expo, the director of IT at a leading genome institute casually remarked that he had just ordered 1.1 petabytes of storage to try to cope with the extraordinary surge in data generation. This puts a premium on sophisticated IT solutions not only for storing data, with reliable and secure backup and retrieval systems. Organizing the data, much of which is generated and viewed once and once only, is a problem that will require more work in future. In this Briefing On supplement, we present a selection of stories published in the past 12-24 months that have examined the technologies that are both creating and solving the next-gen data deluge (“The DNA Data Deluge”).

Increasingly, the value of next-gen sequencing studies is being validated with the identification of rare disease genes in studies of small families (“Next- Generation Genome Sequencing Identifies Disease Genes”). It is possible that the arrival of third-generation sequencing solutions, such as that from Pacific Biosciences (“PacBio’s Eleven”), will reduce the intense need to store image data, but IT managers aren’t popping the champagne corks just yet. One of the most interesting trends in next-gen data management is the potential of “on demand”.

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