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Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Apricot Kernels Pose Risk of Cyanide Poisoning
Eating more than three small raw apricot kernels, or less than half of one large kernel, in a serving can exceed safe levels. Toddlers consuming even one small apricot kernel risk being over the safe level.
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Understanding Female HIV Transmission
Glowing virus maps points of entry through entire female reproductive tract for first time.
Genetic Markers Influence Addiction
Differences in vulnerability to cocaine addiction and relapse linked to both inherited traits and epigenetics, U-M researchers find.
Lab-on-a-Chip for Detecting Glucose
By integrating microfluidic chips with fiber optic biosensors, researchers in China are creating ultrasensitive lab-on-a-chip devices to detect glucose levels.
A lncRNA Regulates Repair of DNA Breaks in Breast Cancer Cells
Findings give "new insight" into biology of tough-to-treat breast cancer.
COPD Linked to Increased Bacterial Invasion
Persistent inflammation in COPD may result from a defect in the immune system that allows airway bacteria to invade deeper into the lung.
Detection of HPV in First-Void Urine
Similar sensitivity of HPV test on first void urine sample compared to cervical smear.
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Advantages of Moving Towards 3-D Scaffolds for Cell Culture
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Nanofiber Solutions

As a biologist, little thought is given to the materials which make up the products that we use in our research day-in and day-out. However, it is these materials which form the ‘building block’ or‘scaffold’ of all cell culture research. The intricate detail going into understanding the cellular response is all dependent on the topographical patterns and surface chemistry of the scaffold used to grow these precious cells. Countless studies have shown the importance of choosing the appropriate tissue culture scaffolds: one that mimics the nanofibrous nature of the extracellular matrix for a wide variety of applications including basic cell biology, drug discovery,tissue engineering, cell migration and invasion, and stem cell expansion and differentiation. Cell culture is mainly performed on tissue culture polystyrene (TCPS) multiwell plates as it is cheap,optically clear, and many cells grow well on it. In reality, however, living organisms are made up of an extracellular matrix that presents both aligned physical structure and support to the cells.

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