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The Rise of 3D Cell Culture and in vitro Model Systems for Drug Discovery and Toxicology
An overview of the current technology and the challenges and benefits over 2D cell culture models plus some of the latest advances relating to human health research.
Grant Supports Project To Develop Simple Test To Screen For Cervical Cancer
UCLA Engineering announces funding from Bill and Melinda Gates Foundation.
Injecting New Life into Old Antibiotics
A new fully synthetic way to make a class of antibiotics called macrolides from simple building blocks is set to open up a new front in the fight against antimicrobial drug resistance.
Insight into Bacterial Resilience and Antibiotic Targets
Variant of CRISPR technology paired with computerized imaging reveals essential gene networks in bacteria.
Advancing Protein Visualization
Cryo-EM methods can determine structures of small proteins bound to potential drug candidates.
Alzheimer’s Protein Serves as Natural Antibiotic
Alzheimer's-associated amyloid plaques may be part of natural process to trap microbes, findings suggest new therapeutic strategies.
Slime Mold Reveals Clues to Immune Cells’ Directional Abilities
Study from UC San Diego identifies a protein involved in the directional ability of a slime mold.
How Do You Kill A Malaria Parasite?
Drexel University scientists have discovered an unusual mechanism for how two new antimalarial drugs operate: They give the parasite’s skin a boost in cholesterol, making it unable to traverse the narrow labyrinths of the human bloodstream. The drugs also seem to trick the parasite into reproducing prematurely.
Illuminating Hidden Gene Regulators
New super-resolution technique visualizes important role of short-lived enzyme clusters.
Supressing Intenstinal Analphylaxis in Peanut Allergy
Study from National Jewish Health shows that blockade of histamine receptors suppresses intestinal anaphylaxis in peanut allergy.
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Highly Reproducible Gene Delivery for Stem Cell Research
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AMSBIO

AMSBIO have announced a range of ready-touselentivirus supernatant products suitablefor many kinds of gene delivery applicationsincluding mammalian protein expression, stablecell line construction, cell signal pathwaylocalization and stem cell research.Converting fully differentiated mouse or humansomatic cells into embryonic-like cells (so calledinduced Pluripotent Stem Cell: iPSC) hasattracted enormous attention in stem cellresearch. Multiple reports have demonstrated thatiPS cells were generated by using a set oftranscription factors or stem cell factors thatdelivered as expression virus or expressedproteins. Although the combination ofreprogramming factors may slightly different, themain stem cell factors are: OCT3/4, SOX2,NANOG, LIN28, c-Myc and KLF4. iPSC holds thepromise of curing many human diseases andaccelerates the stem cell research.

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