Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Evotec AG: New Hormone to Treat Diabetes Published in “Cell”

Published: Friday, April 26, 2013
Last Updated: Friday, April 26, 2013
Bookmark and Share
Harvard University Prof. Doug Melton and his post doc Peng Yi describe the new hormone “betatrophin” that controls beta cell proliferation as potential diabetes treatment.

Evotec AG announced an auspicious step in research from Harvard University. The findings are published in a scientific article by Prof. Doug Melton, University professor at Harvard University and Howard Hughes Medical Institute (HHMI) investigator and his post doc Peng Yi in the journal Cell. Doug Melton is the academic key collaborator of CureBeta, a strategic alliance between Harvard University, Evotec and Janssen Pharmaceuticals in the field of beta cell regeneration.

In the article, available as of 25 April 2013 in the online edition of Cell ,Doug Melton, who is also the co-director of the Harvard Stem Cell Institute and his post doc Peng Yi release the discovery of the new hormone betatrophin that controls beta cell proliferation. All intellectual property associated with these findings have been licensed to Evotec in March 2011 and subsequently sublicensed to Janssen Pharmaceuticals within the CureBeta collaboration announced in July 2012.

Dr Cord Dohrmann, Chief Scientific Officer of Evotec, commented: “Restoring beta cell mass and function is the most promising approach to slow down or reverse disease progression in diabetic patients. The laboratory of Doug Melton has made a series of important contributions to this beta field in particular demonstrating that beta cell proliferation is a key mechanism that controls beta cell mass. His latest publication describes a previously underappreciated capacity of beta cells to proliferate in response to a pharmacological trigger and the identification of a novel physiological mediator, betatrophin.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Evotec and Harvard University to Collaborate
The partnership will explore enteroendocrine signals affecting key metabolic pathways.
Thursday, October 10, 2013
Evotec and Harvard Stem Cell Institute form CureMN Collaboration to Advance ALS Research
Strategic partnership established with the Harvard Stem Cell Institute (“HSCI”) to identify compounds that prevent or slow down the loss of motor neurons.
Thursday, September 12, 2013
Evotec Acquires Compound Management Business from Galapagos
Evotec to further strengthen its integrated innovation offering with world-class compound management.
Thursday, June 02, 2011
Scientific News
A Boost for Regenerative Medicine
Growing tissues and organs in the lab for transplantation into patients could become easier after scientists discovered an effective way to produce three-dimensional networks of blood vessels, vital for tissue survival yet a current stumbling block in regenerative medicine.
Heart Defect Prediction Technology Could Lead to Earlier, More Informed Treatment
Experimental method uses genetics-guided biomechanics, patient-specific stem cells.
Immune Cells Remember Their First Meal
Scientists at the University of Bristol have identified the trigger for immune cells' inflammatory response – a discovery that may pave the way for new treatments for many human diseases.
Cancer Cells Coordinate to Form Roving Clusters
Rice University scientists identify ‘smoking gun’ in metastasis of hybrid cells.
Bio-Mimicry Method For Preparing & Labeling Stem Cells Developed
Method allows researchers to prepare mesenchymal stem cells and monitor them using MRI.
Transcription Factor Isoforms Implicated in Colon Diseases
UC Riverside study explains how distribution of two forms of a transcription factor in the colon influence risk of disease.
New Bio-Glass Could Make it Possible to Re-Grow or Replace Cartilage
Researchers at Imperial College London have developed a material that can mimic cartilage and potentially encourage it to re-grow.
Stem Cell Advance Could Be Key Step Toward Treating Deadly Blood Diseases
UCLA scientists get closer to creating blood stem cells in the lab.
Harnessing Engineered Slippery Surfaces For Tissue Repair
A new method could facilitate the transfer of intact regenerating cell sheets from the culture dish to damaged tissues in patients.
Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models
First direct experimental proof of causal effect, researchers say.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!