Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
Scientific Community
Become a Member | Sign in
Home>News>This Article

Life Technologies Launches Industry's First Stem Cell Characterization Panel

Published: Monday, June 17, 2013
Last Updated: Monday, June 17, 2013
Bookmark and Share
Developed with Harvard University, TaqMan® hPSC Scorecard™ Panel provides a benchmark against which researchers can evaluate pluripotency and potential of cell lines.

Life Technologies Corporation has launched the TaqMan® hPSC Scorecard™ Panel, a first-of-its-kind characterization assay that establishes a standardized benchmark against which researchers can now evaluate pluripotency and trilineage differentiation potential in human embryonic (ES) and induced pluripotent stem (iPS) cell lines.

Life will showcase the technology during the International Society for Stem Cell Research (ISSCR) conference in Boston June 12-15.

Until now, scientists have evaluated pluripotency - the potential for ES and iPS cells to differentiate into any cell type - with laborious, costly and non-standardized methods that provide ambiguous results.

Additionally, their inability to accurately determine cell lines' propensity to differentiate into one of the three primary cell germ layers has contributed to major hurdles that impede stem cell technology from moving into the clinic.

The TaqMan® hPSC Scorecard™ Panel, however, relies on a specific range of gene expression levels identified at Harvard University to accurately characterize cell lines in two critical areas: pluripotency and lineage bias.

The panel is also being offered with cloud-based software for rapid data analysis and data sharing among research collaborators.

"The rapid advancements in stem cell research over the last few years have created a need for more effective and standardized methods for characterizing pluripotent cells," said Alex Meissner, Ph.D., Associate Professor, Department of Stem Cell and Regenerative Biology, Harvard University.

Meissner continued, "Today, the field of genomics is helping to meet that demand through development of novel approaches that can help deliver the promise of stem cells."

Life Technologies developed the TaqMan® hPSC Scorecard™ Panel in collaboration with Dr. Meissner. He is the lead author of a study in the journal Cell (Vol. 144, No. 3, pp. 439-452, Feb. 4, 2011) who identified a range of expression levels among key genes associated with pluripotency.

By measuring gene activity in ES and iPS cells against the study's gene expression range, Dr. Meissner's lab was able to accurately score cells for their potential to differentiate into particular cell lineages.

Standardizing characterization allows researchers to work more efficiently by enabling them to quickly identify the most promising cells.

It also helps accelerate various applications, including development of "disease-in-a-dish" models from patient-derived cells, drug screening and eventual use of pluripotent cells as a renewable source for transplantation medicine.

"It has become increasingly critical for researchers to consistently and accurately characterize the cells they are working with, particularly to realize the promise of stem cell-based technology in drug discovery and clinical applications," said Chris Armstrong, Ph.D., General Manager and Vice President of Primary and Stem Cell Systems at Life Technologies.

Armstrong continued, "As such, the launch of this novel characterization panel supports our continued commitment to provide our customers with the most innovative products across the pluripotent stem cell workflow."

Dr. Meissner will give a presentation on his lab's use of the TaqMan® hPSC Scorecard™ Panel during one of two Innovation Showcases Life Technologies will host at ISSCR in Room 257 A-B on June 14. His talk takes place from 12:30-1 p.m.

The second Innovation Showcase will feature Dr. Birgitt Schuele, M.D., Assistant Professor, Clinical Molecular Geneticist, The Parkinson's Institute, who will present her lab's use of Sendai virus-based CytoTune® reprogramming technologies to recapitulate phenotypes associated with Parkinson's Disease.

Her presentation will take place from 11:45 a.m.-12:15 p.m. For more information on the Innovation Showcases, visit the Life Technologies ISSCR booth (# 630).

TaqMan® hPSC Scorecard™ Panel is For Research Use Only, not intended for diagnostic purposes.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Life Technologies Extends Partnership with DNAVEC
R&D collaborative agreement aims to further develop Sendai virus-based tools for basic and translational research.
Monday, October 21, 2013
Life Technologies Announces Second Quarter 2013 Results
Revenue increased 1% excluding impact of currency.
Thursday, August 01, 2013
Life Technologies Acquires KDR Biotech
The acquisition is part of Life Technologies strategic international growth plan in fast-growing markets.
Friday, April 12, 2013
Life Technologies Signs Stem Cell Agreement with Harvard University
Research collaboration aimed at yielding standardized method for evaluating iPS cell quality; deepens Life's investment to its expanding stem cell product portfolio.
Tuesday, March 05, 2013
Life Technologies Names Alan Sachs as Head of Global Research and Development
Sachs brings more than 20 years of experience as a research scientist and a leader in developing innovative scientific platforms.
Wednesday, February 01, 2012
Scientific News
Urine Excretion From Stem Cell-Derived Kidneys
Researchers report a strategy for enabling urine excretion from kidneys grown from stem cells.
Stem Cell Research Hints at Evolution of Human Brain
Researchers at UC San Francisco have succeeded in mapping the genetic signature of a unique group of stem cells in the human brain that seem to generate most of the neurons in our massive cerebral cortex.
The Final Word on STAP
Researchers fail to replicate STAP study; computational analysis reveals genomic inconsistency.
CRI Scientists See Through Bones
Findings uncover new details about blood-forming stem cells.
Scientists Sequence Genome Of Worm That Can Regrow Body Parts
Worm’s genome could lead to better understanding of its regenerative prowess and advance stem cell biology.
Stem Cell-Derived 'Organoids' Help Predict Neural Toxicity
A new system developed by scientists may provide a faster, cheaper and more biologically relevant way to screen drugs and chemicals that could harm the developing brain.
New Way To Repair Nerves
Tufts University biomedical engineers recently published the first report of a promising new way to induce human mesenchymal stem cells to differentiate into neuron-like cells:treating them with exosomes.
Pancreatic Cancer Stem Cells Could be "Suffocated" by Anti-diabetic Drug
A new study shows that pancreatic cancer stem cells (PancSCs) are virtually addicted to oxygen-based metabolism, and could be “suffocated” with a drug already used to treat diabetes.
Filling A Void In Stem Cell Therapy
A new porous hydrogel could boost the success of stem-cell-based tissue regeneration.
Diabetes Research Institute's First Patient In Biohub Trial No Longer Requires Insulin Therapy
New transplant technique restores natural insulin production in type 1 diabetes.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos