|Integrating compound storage into automated laboratory workflows |
James Craven, Simon Tullett
This poster discusses the benefits of comPOUND for automated sample storage and delivery. TTP Labtech’s pneumatic transport technology, lab2lab, integrates these stores with other instrumentation into managed, fully automated workflows, allowing the scientist to focus on research and data analysis.
|Chia-Hsun Hsieh and Sanger Hung-Chih Lin win at CellTech |
Sanger Hung-Chih Lin, Chia-Hsun Hsieh, Hung-Chih Hsu, Hung-Ming Wang, Chi-Ya Huang, Min-Hsien Wu and Ching-Ping Tseng
Chia-Hsun Hsieh and Sanger Hung-Chih Lin win at CellTech
|Low cost, low footprint, expandable automated biobanking solutions |
James Craven, Chris Morris, Maud Godfrey, Danielle Miller
This case study describes how TTP Labtech’s comPOUND storage modules have been employed by Abcam, a worldwide supplier of antibodies. Here, the turnaround time of sample placement and retrieval is an essential component for high quality service to its customers.
|Gene Expression from Pseudourine and 5-Methylcytidine Modified Messenger RNA|
Jiehua Zhou, Maggie L. Bobbin, Julie R. Escamilla-Powers, Anton P. McCaffrey and John J. Rossi
Study objective was to develop methodologies for gram scale synthesis of messenger RNA (mRNA) for gene therapy applications, as well as scalable purification methods that yield highly expressed, persistent and non-toxic mRNA.
|ISMTR-283 Protects Human Bone Marrow Progenitors from the Lethal Effects of Ionizing Radiation|
Clarke E, Traynor-Kaplan A
Bone Marrow (BM) is extremely susceptible to radiation damage. BM from matched donors is often used to ‘rescue’ patients following medical radiation for leukemia. However, in the event of accidental/environmental radiation exposure, the ability to identify appropriate donors in a timely manner is rarely possible. Using CFC assays, we evaluated a small molecule compound (ISMTR-283) for its potential to protect the marrow progenitor cells and microenvironment from radiation damage.
|Analyzing Molecular Polar Surface Descriptors to Predict Blood-Brain Barrier Permeation|
Sergey Shityakova, Winfried Neuhausa, Thomas Dandekarc and Carola Förstera
Permeation of active drugs across the vascular brain endothelium into the central nervous system (CNS) is controlled by the blood-brain barrier (BBB). Some molecular quantities like polar surface (PS) descriptors are of key interest to medicinal chemists to predict the BBB permeation fate for different drug-like chemical compounds.
|The Mesenchymal Stem Cells Bioengineered Tissue Using Cobalt-60 Radiation|
Mosca, RC., Isaac, C., Mathor, MB
The biological effects of gamma radiation by cobalt-60 sources on epidermal-dermal matrix have not been fully elucidated when mesenchymal stem cells cultured add in. This poster shows how scientists standardized the keratinocytes and adipose-derived stem cell (ADSC) culture procedure before constructing a bioengineered dermal-epidermal equivalent populated by keratinocytes and ADSC cultured cells.
|Expression of Pluripotency-determining Factors in in vitro Fertilized Buffalo Embryos and Embryonic Stem Cells|
T Anand, D Kumar, M S Chauhan, and P Palta
The POU octamer-binding domain transcription factor Oct-4, Stage-specific embryonic antigens (SSEAs), and Tumor rejection antigens (TRAs), are developmentally regulated during early embryogenesis.
|Effect of Culture Media and Serum Supplementation on the Development of in vitro Fertilized Buffalo Embryos|
D Kumar, T Anand, P Palta and M.S. Chauhan
This poster compares the development of buffalo embryos in simple and complex culture media and aims to determine the effects of serum supplementation on the development of buffalo embryos.