Corporate Banner
Satellite Banner
Scientific Communities
Become a Member | Sign in
Home>Videos>This Video


Improvements in Molecular Diagnosis of Pathogens and Diseases

Loop-mediated Isothermal Amplification (LAMP) belongs to a range of main current and new diagnostic techniques for early-stage detection of pathogens such as viruses, bacteria, fungi, protozoa, worms, amongst other. In addition, molecular recognition of cancer, genetic disorders and species determination or sex determination of organisms has also achieved by LAMP. The LAMP reaction was found to be superior over the Polymerase Chain Reaction (PCR) in most cases with respect to detection limit, sensitivity, specificity and usefulness. The superior capability of LAMP relies on the application of primer sets consisting of four to six designated primers that recognize certain regions of the target nucleic acid sequence and on the incorporation of Bst DNA polymerase capable of splicing DNA strands. We can expect that research on and application of the LAMP method will take a course that is similar to that of the PCR method during the last decades, which means improvement of its already high sensitivity and specificity, improvement of its multiplexing capability, extension of its application fields to both highly specialized detection tasks and fields of economic interest and further cost reduction. This presentation will offer a valuable guide to the development of LAMP in molecular detection and determination of target sequences and will present examples with bright field applications of the method from the detection of pathogens to clinical applications for the diagnosis of cancer and other disorders according to current stage of this well-accepted methodology by the scientific community during the last decade.

Request more information
Company product page

Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
Dr John Comley provides an insight into HT MS-based screening with a focus on future user requirements and preferences.
How a Genetic Locus Protects Adult Blood-Forming Stem Cells
Mammalian imprinted Gtl2 protects adult hematopoietic stem cells by restricting metabolic activity in the cells' mitochondria.
Genetic Basis of Fatal Flu Side Effect Discovered
A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a recent study.
New Tech Vastly Improves CRISPR/Cas9 Accuracy
A new CRISPR/Cas9 technology developed by scientists at UMass Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.
The MaxSignal Colistin ELISA Test Kit from Bioo Scientific
Kit can help prevent the antibiotic apocalypse by keeping last resort drugs out of the food supply.
"Good" Mozzie Virus Might Hold Key to Fighting Human Disease
Australian scientists have discovered a new virus carried by one of the country’s most common pest mosquitoes.
Non-Disease Proteins Kill Brain Cells
Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos