The PromethION is Oxford Nanopore Technologies' largest sequencing device, capable of delivering many terabases of data, in real time, from a single run. Hear how teams across a broad range of applications, based in labs all over the world — US (UCSF, UCD, JCVI and UCSC), China (GrandOmics and Biomarker) and Europe (KeyGene, Genescope and UMC Utrecht) — are using PromethION in their work.

In this video, Sophie discusses the 'biomarkers' which could be used to spot Alzheimer's in its early stages.

The introduction of exome analysis provides the opportunity to improve more findings compared to traditional genetic testing approaches and fixed panel-based genomic analyses. Large studies of many families using trio exomes and a genotype first approach have been incredibly powerful tools for gene discovery and identification of pathogenic variants in rare Mendelian disorders. Proband only exomes, however, require different methods of variant filtering which typically involve prioritisation of genes and/or variants based on phenotype.

Designed to address processing efficiency, reproducibility, and robustness of results, the iWestern Workflow helps to enable exceptional western blot results with minimal hands-on time.