Handy Homogeniser Simplifies Cannabis Sample Preparation
The Chromatrap Spin Column Homogeniser from Porvair Sciences is the tool of choice for labs preparing Cannabis samples for analysis of Tetrahydrocannabinol (THC) and Cannabidiol (CBD).
Boost the Boundaries of Early Drug Discovery
Dynamic injection technology provides rapid hit selection and complete evaluation of fragment actives. No other SPR system provides this acceleration of the FBDD process replacing the need for secondary screens for hit validation. A competitive assay can complement the evaluation of fragment actives by binding site on the target protein.
Mental Fatigue May Involve a Potentially Toxic Chemical Buildup in the Brain
A workday doesn’t have to involve tiring manual labor to leave you feeling exhausted. A new study claims to have pinned down a functional reason why we feel fatigued after a day of mental effort.
How the Brain Performs Pattern Recognition Without Us Noticing
Human brains learn patterns over time and we don’t even realize it. New insight into how this works could improve learning and other cognitive processes.
Could the Brain's Cleaning Crew Mop Up Alzheimer's?
The microglia – cells in the brain responsible for clearing waste and toxins – can change state in Alzheimer's disease and contribute to neuroinflammation, but researchers have found a way of reprogramming these cells.
Radically Rethinking Scientific Publication: The “Octopus” Model
Dr. Alexandra Freeman believes that the major problems associated with research culture in science can be traced back to one source: the current scientific publishing model. In this interview with Technology Networks, she explains why a novel approach, called Octopus, is a logical solution to these issues.
3D Cell Culture: Will Organoids Add a New Dimension to Disease Modeling?
This article explores the world of organoids, their benefits and limitations, and where they may play a role in the future of disease modeling.
The Growing Importance of Mitochondrial Toxicity Assessment in Drug Discovery and Development
The pharmaceutical industry spent decades bringing several drugs to the market, only to be withdrawn due to liver failure, associated with mitochondrial toxicity. The tests available at the time could not detect this toxicity and drug developers were presented a market withdrawal risk.
How To Address NGS Challenges
Download this guide to learn how to select the appropriate NGS method and sequencing platform, deal with samples of variable quality, and set up and manage the data analysis pipeline.
Clinical Applications of Cell Therapy
Download this listicle to explore cell therapy applications including oncology, neurodegenerative disease and diabetes.
Spatial Transcriptomics: Understanding Gene Regulation in the Tissue Context
Download this listicle to explore spatial transcriptomics applications and key technologies including next-generation sequencing based-methods, In situ sequencing-based methods and In situ hybridization-based methods.
Standardizing Analytical Data With AnIML
This listicle presents AnIML — an open XML-based, vendor-neutral and human-readable file format that can be used to store data from different analytical instruments. This facilitates the achievement of FAIR (i.e., findable, accessible, interoperable and reusable) data which is a prerequisite for proper data management, data stewardship and a successful digital transformation strategy.