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The Brain Bounces Back: Activity enables mice to overcome brain damage

Article

Scientists removed an area of the somatosensory cortex in mice and found the animals could recover their behavioral deficit within two days.

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PromethION in action, in labs around the world

Video

The PromethION is Oxford Nanopore Technologies' largest sequencing device, capable of delivering many terabases of data, in real time, from a single run. Hear how teams across a broad range of applications, based in labs all over the world — US (UCSF, UCD, JCVI and UCSC), China (GrandOmics and Biomarker) and Europe (KeyGene, Genescope and UMC Utrecht) — are using PromethION in their work.

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The Biomarkers Which Could be Used to Spot Alzheimer’s Earlier

Video

In this video, Sophie discusses the 'biomarkers' which could be used to spot Alzheimer's in its early stages.

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Customizing The Exome

Webinar

The introduction of exome analysis provides the opportunity to improve more findings compared to traditional genetic testing approaches and fixed panel-based genomic analyses. Large studies of many families using trio exomes and a genotype first approach have been incredibly powerful tools for gene discovery and identification of pathogenic variants in rare Mendelian disorders. Proband only exomes, however, require different methods of variant filtering which typically involve prioritisation of genes and/or variants based on phenotype.

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Streamline your western blotting workflow with iWestern

Featured Product

Designed to address processing efficiency, reproducibility, and robustness of results, the iWestern Workflow helps to enable exceptional western blot results with minimal hands-on time.

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Treatment for Canine Leishmaniasis Exists in Brazilian Vaccine

Treatment for Canine Leishmaniasis Exists in Brazilian Vaccine

News

Canine leishmaniasis, typically transmitted by sand fly bites, can cause skin sores, weight loss, blindness and kidney failure.

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Researchers Find Inhibiting One Protein Destroys Toxic Clumps Seen in Parkinson's Disease
News

“To our knowledge, these data are the first to elucidate the role of USP13 in neurodegeneration.”

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Membrane Proteins Ejected Directly from Cell Membrane to Mass Spec
News

A new approach to analyzing cell membrane proteins in situ could revolutionize the way in which we study diseases, such as cancer, metabolic and heart diseases.

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Arming Drug Hunters: Chemists design new reaction for drug discovery
News

The pair of Colorado State University organic chemists have forged a powerful new tool for drug hunters - a simple, elegantly designed chemical reaction that could fling open an underexplored wing of biologically relevant chemistry.

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Using Supercomputers to Predict Dispersal of Chemicals and Pollutants

Using Supercomputers to Predict Dispersal of Chemicals and Pollutants

Article

Motivated by a deadly chemical attack in Syria, researchers at the University of Texas at San Antonio are pursuing research that may help save lives during an airborne chemical attack. The team used the Stampede2 supercomputer and innovative computer simulation models to replicate the dispersion of the chemical gas released in the Syrian event, which may help improve evacuation speed during future attacks.

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Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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'Microdosers' of LSD and Magic Mushrooms are Wiser and More Creative
Article

Researchers just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results.

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Overcoming Western Blot Reproducibility Problems: Tips for Producing More Accurate and Reliable Data
Article

This article outlines key workflow steps to help researchers perform better western blots. By executing best practices in these steps – sample preparation, gel electrophoresis, gel transfer, protein detection, and image analysis – researchers can expect good western blot data.

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