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Customizing The Exome

Webinar

The introduction of exome analysis provides the opportunity to improve more findings compared to traditional genetic testing approaches and fixed panel-based genomic analyses. Large studies of many families using trio exomes and a genotype first approach have been incredibly powerful tools for gene discovery and identification of pathogenic variants in rare Mendelian disorders. Proband only exomes, however, require different methods of variant filtering which typically involve prioritisation of genes and/or variants based on phenotype.

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iBright Imaging Systems

Video

Capture images and analyze data from your western blots and gels efficiently and easily using the Invitrogen iBright Imaging Systems.

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Using Supercomputers to Predict Dispersal of Chemicals and Pollutants

Article

Motivated by a deadly chemical attack in Syria, researchers at the University of Texas at San Antonio are pursuing research that may help save lives during an airborne chemical attack. The team used the Stampede2 supercomputer and innovative computer simulation models to replicate the dispersion of the chemical gas released in the Syrian event, which may help improve evacuation speed during future attacks.

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Exploring multiple dimensions in the forensics of “space candy”

Video

In #BehindtheScience, Jen travels to Boston University's outdoor research facility, where grad students and law enforcement are trained on crime scene investigation. Is it possible to use one analytical technique to test a variety of different matrices - liquid or solid?

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Saliva-based Biomarkers and Algorithm Could Aid Autism Diagnosis

Saliva-based Biomarkers and Algorithm Could Aid Autism Diagnosis

News

A saliva-based biomarker panel and algorithm could help fast-track the identification of children who are suspected of having autism spectrum disorder.

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How Fast you Walk Says a Lot About Your Health
News

Researchers use gait speed as a way to identify patients who might have difficulties recovering from surgery, or other health issues.

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AI-Capnograph Distinguishes Between Emphysema and Heart Failure
News

By analyzing carbon dioxide in the breath, an algorithm could help determine how to treat patients.

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Machine-learning System Could Aid Critical Decisions in Sepsis Care
News

This predictive model could guide clinicians in deciding when to give potentially life-saving drugs to patients being treated for sepsis in the emergency room.

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Unlocking the Secrets of Brain Organization -in the Fruit Fly

Unlocking the Secrets of Brain Organization -in the Fruit Fly

Article

As many people spent the summer trying to keep the flies away from their fruit-bowls, an international group of scientists published one of the biggest and most important datasets in the field of connectomics to date, the complete 3D electron micrograph volume of the fruit-fly (Drosophila melanogaster) brain.

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Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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'Microdosers' of LSD and Magic Mushrooms are Wiser and More Creative
Article

Researchers just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results.

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Overcoming Western Blot Reproducibility Problems: Tips for Producing More Accurate and Reliable Data
Article

This article outlines key workflow steps to help researchers perform better western blots. By executing best practices in these steps – sample preparation, gel electrophoresis, gel transfer, protein detection, and image analysis – researchers can expect good western blot data.

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