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Fragment-based Drug Discovery

Infographic

In this infographic, we review the history of fragment-based drug discovery, discuss the underlying concepts and examine the process in more detail.

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Moving Ions Around Corners To Revolutionize Disease Detection and Biotherapeutic Development

Industry Insight

The study of proteins, lipids, metabolites and other related molecules are invaluable in early disease detection and biotherapeutic development. An innovative separation technology borne out of a US Federal Laboratory, known as structures for lossless ion manipulation, is helping scientists to achieving this.

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Simulating the Brain: The Markram Interviews

Article

The EPFL Blue Brain Project (BBP) is a Swiss National Research Infrastructure project which has spent the last 15 years trying to advance the cause of simulation neuroscience. Through successes and headwinds, the BBP has been led since inception by Professor Henry Markram. The first part of our exclusive interview series with Markram is an introduction to simulation neuroscience. Read it now.

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Never Miss a Moment with the MuviCyte Live-Cell Imaging System from PerkinElmer

Video

The MuviCyte system is designed to operate inside your incubator, so you can maintain your cells under optimal conditions, keeping them healthy for weeks at a time.

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Merging Spectroscopy Methodologies Enables Study of Superheavy Elements

News

Researchers present a concept for a new technique to study superheavy elements, challenging and intriguing nuclear and atomic quantum systems, by merging methodologies from physics and chemistry for optical spectroscopy.

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First Complete Human X Chromosome Sequence Generated
News

Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, have produced the first end-to-end DNA sequence of a human chromosome.

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Phase 1 Clinical Trial of University of Queensland COVID-19 Vaccine Begins
News

The first participants were enrolled into a Phase 1 clinical trial of the University of Queensland’s (UQ) COVID-19 vaccine candidate on July 13.

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Collagen V Regulates Cardiac Scar Tissue Size
News

Researchers from the Terasaki Institute for Biomedical Innovation have identified that type 5 collagen regulates the size of scar tissue formed after injury to the heart.

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Bristol University Brain Imaging Center Slated To Close, Putting 95% of Projects at Risk

Article

Bristol University have announced that the Clinical Research and Imaging Center (CRICBristol), a joint venture with University Hospitals Bristol NHS Foundation Trust, will close at the end of December, putting six jobs at risk and throwing dozens of research projects into jeopardy.

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Sequencing the Human Microbiome: Opening the Black Box
Article

Researchers are using sequencing technologies to rapidly expand our knowledge of the human microbiome and identify undiscovered bacterial genomes.

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The Markram Interviews Part One: An Introduction to Simulation Neuroscience
Article

In the first of our exclusive three-part interview series with Blue Brain Project Founder and Director Professor Henry Markram, we discuss the basics of simulation neuroscience. Markram, one of the leading proponents of the field, comments on why the idea of simulating the brain has raised concerns from experimental and theoretical neuroscientists and answers whether in silico techniques could ultimately replace experimental approaches.

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Advances in Phenotypic Screening: A Turning Point for Drug Discovery?
Article

In this article, we explore recent developments related to cell-based phenotypic screening, discuss the elements of a good phenotypic drug screen, and discover how these approaches are helping to provide a more accurate biological context for drug screening.

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