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Can High-Throughput Technologies Improve Reproducibility in Neuroscience?

Article

By improving sensitivity in quality control, increasing capacity and throughput, and by improving assay development and measurement, high-throughput technologies are helping to overcome the reproducibility crisis in science.

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The 1918 Flu Pandemic

Infographic

The global flu pandemic of 1918, dubbed “Spanish flu”, killed 50 million people worldwide including the young, fit and healthy. Here we highlight some of the key events of the pandemic.

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8 Tips for Improving Your NGS Libraries

List

For most laboratory workflows, you’re only as good as your starting material. This is particularly true for next-generation sequencing (NGS). Library quality is all-important in ensuring you receive high quality data.

Whilst each platform and each type of NGS experiment will require its own optimization, there are several tips and tricks to preparing NGS libraries that hold true across all applications, which we've complied in this handy list.

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Clearest Ever Image of Ebola Virus Protein

Clearest Ever Image of Ebola Virus Protein

News

The structure of a central component of the Ebola virus has been imaged for the first time at near-atomic resolution.

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Progress in Cochlear Regeneration
News

This research demonstrates a signaling pathway that can be activated by different methods and could represent a new approach to cochlear regeneration and, ultimately, restoration of hearing.

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How the Brain's Epigenetic Factors Change in Alzheimer's
News

Pioneering research into the mechanisms controlling gene activity and epigenetic factors in the brain could hold the key to understanding Alzheimer’s disease and might help identify effective treatments in the future.

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How Does the Black Widow Get Its Strength?
News

Scientists have unraveled the complex process of how black widow spiders transform proteins into steel-strength fibers, aiding strong synthetic material synthesis.

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Exploring Consciousness with Psychedelics

Exploring Consciousness with Psychedelics

Article

Chris Timmermann, from The Psychedelic Research group at Imperial College London studies the action of psychedelics on the brain and their potential as therapeutics. This article reviews their research and their implications.

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Exploiting Epigenetics in Cancer Treatment
Article

Changes to the complex of DNA and the proteins that form chromatin are important drivers in many cancers. We explore the challenges and progress in the development of new therapies targeting epigenetic regulators.

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Through the Looking Glass of Single Cell Proteomics
Article

To pick apart the differences between individual cells in complex multicellular organisms, we need to look at cells one-by-one. This article takes a look at how several scientists in North America are using single cell proteomics (SCP) technologies to discern disease pathogenesis and enhance directed stem-cell differentiation.

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Exploring the Public’s Perception of Food Fraud
Article

When you go to the shops to buy the weekly groceries, it’s quite likely you’ll find yourself thinking about where your food has come from. Is this organic? Is that free-range? You are perhaps less likely to find yourself wondering, “Is this food fake?”

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