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Developing an HIV vaccine

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Professor Robin Weiss and Dr Laura McCoy explain some of the processes and challenges involved in developing an HIV vaccine.

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Streamline your western blotting workflow with iWestern

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Designed to address processing efficiency, reproducibility, and robustness of results, the iWestern Workflow helps to enable exceptional western blot results with minimal hands-on time.

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Bacteriophage – A Virus that Infects Microbes

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To reproduce, bacteriophage infect bacterial cells and hijack their cellular machinery before killing their host as shown in this animation.

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Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd

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Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry.

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Identify and Quantify Individual Host Cell Proteins

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ELISA is the golden standard for HCP analysis but has some drawbacks. It only provides a single number (ng HCP/mg drug substance) and no information about the specific HCP’s.

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Crystal Structure Predictor Inspired by Nature

Crystal Structure Predictor Inspired by Nature

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Scientists found a way of improving the crystal structure prediction algorithms, making the discovery of new compounds many times faster.

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Membrane Proteins Ejected Directly from Cell Membrane to Mass Spec
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A new approach to analyzing cell membrane proteins in situ could revolutionize the way in which we study diseases, such as cancer, metabolic and heart diseases.

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Arming Drug Hunters: Chemists design new reaction for drug discovery
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The pair of Colorado State University organic chemists have forged a powerful new tool for drug hunters - a simple, elegantly designed chemical reaction that could fling open an underexplored wing of biologically relevant chemistry.

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Drug Candidate Could Recover Vocal Abilities Lost to ADNP Syndrome
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A new Tel Aviv University study finds that the drug candidate CP201, also known as NAP, may improve vocal communication abilities that are underdeveloped in Activity-dependent neuroprotective protein (ADNP) patients.

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Artificial Intelligence, Real Solutions: How AI Can Accelerate Drug Discovery

Artificial Intelligence, Real Solutions: How AI Can Accelerate Drug Discovery

Article

The rate at which new drugs are discovered is in decline, and computer-aided drug design has not produced the radical change in the success of candidate drugs the pharma industry anticipated. Artificial intelligence (AI)-based approaches are the new hope for revolutionizing the drug discovery process. But are these, as computer-aided drug design was, an over-hyped time bomb waiting to be found out? Or is it truly a revolution on the cusp of realizing its promise?

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Using Supercomputers to Predict Dispersal of Chemicals and Pollutants
Article

Motivated by a deadly chemical attack in Syria, researchers at the University of Texas at San Antonio are pursuing research that may help save lives during an airborne chemical attack. The team used the Stampede2 supercomputer and innovative computer simulation models to replicate the dispersion of the chemical gas released in the Syrian event, which may help improve evacuation speed during future attacks.

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Care in the Community – How Biofilms Improve Bacterial Survival
Article

A single bacterial cell on its own is vulnerable to attack and like many living things they can benefit from safety in numbers. But bacteria take communal living to a whole new level, forming veritable civilizations - the bacterial biofilm.

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'Microdosers' of LSD and Magic Mushrooms are Wiser and More Creative
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Researchers just ran the first ever pre-registered scientific study on the microdosing of psychedelics and found some very promising results.

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