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Identify and Quantify Individual Host Cell Proteins

Webinar

ELISA is the golden standard for HCP analysis but has some drawbacks. It only provides a single number (ng HCP/mg drug substance) and no information about the specific HCP’s.

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ELN, LIMS, CDS, LES: What’s the Difference?

Article

In this article, we look at the key differences between four common types of informatics systems. CSols Inc. is an independent informatics consultancy, and their Delivery Manager, Geoff Turnbull, will help us answer some important questions on the role these systems play, where they overlap with each other, and why we don’t just have one overarching system to rule them all.

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Bioengineering and Food Labeling Requirements

Article

In a move aimed to make the origins of food more transparent for consumers, the USDA have launched new rulings regarding the labeling requirements for bioengineered ingredients – but what does this mean for producers, retailers and consumers?

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Understanding P-gp and BCRP Inhibition Assay Design and Outcomes

Video

Key concepts discussed in this webinar will include: - Description of the in vitro test systems used to evaluate P-gp and - BCRP inhibition at Sekisui XenoTech and the advantages/disadvantages of these assays - Description of the test system qualification process that takes places prior to offering these assays in definitive studies - Comparison of IC50 values obtained from the different test systems - Comparison of IC50 and Ki values determined with the vesicle test system - How IC50 and Ki values are used to evaluate clinical relevance

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Anonymous Yet Trustworthy

Anonymous Yet Trustworthy

News

Minority and dissident communities face a perplexing challenge in countries with authoritarian governments. They need to remain anonymous to avoid persecution, but also must establish a trustworthy identity in their communications. An interdisciplinary group of researchers at UC Santa Barbara has designed an application to meet both of these requirements.

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Novelty in Plants: The Effects of Genome Doubling
News

Researchers examine the effects of genome doubling on cell biology and the generation of novelty in plants.

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The 17 Different Ways Your Face Conveys Happiness
News

Human beings can configure their faces in thousands and thousands of ways to convey emotion, but only 35 expressions actually get the job done across cultures, a new study has found.

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Making Plastic from Poo!
News

A new, fossil-free bioplastic is emerging. According to lab experiments, it is more durable than both regular plastic and other bioplastics, and is potentially better suited for recycling.

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Unlocking the Secrets of Brain Organization -in the Fruit Fly

Unlocking the Secrets of Brain Organization -in the Fruit Fly

Article

As many people spent the summer trying to keep the flies away from their fruit-bowls, an international group of scientists published one of the biggest and most important datasets in the field of connectomics to date, the complete 3D electron micrograph volume of the fruit-fly (Drosophila melanogaster) brain.

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Microglia Transmit Pain to the Brain During Stress
Article

Chronic pain is a multifaceted disorder that causes profound disability worldwide. It has long been known that psychological stress contributes to adverse chronic pain outcomes in patients, but it is unclear how this is initiated or amplified by stress. Now, researchers have published results showing that activation of microglia in the mouse spinal cord is responsible for increased pain sensitivity in response to stress.

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Building Blocks for a Greener Future
Article

At a time when plastic use is coming under great scrutiny, what are LEGO, whose foundations are built on plastic products, doing to alleviate the problem? We spoke to Tim Brooks, VP Environmental Responsibility for LEGO Group about their commitment to use sustainable materials in core products and packaging by 2030.

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Mass Spectrometry’s Important Role in Identifying Explosives in the Environment
Article

Explosives, especially when not contained or disposed of correctly, pose a significant hazard to humans, wildlife and the ecosystem. Having the tools to be able to identify their presence and state are therefore key to combating the issue. We spoke to Stanislaw Popiel about the game-changing role that mass spectrometry is playing in the process and some of the challenges that still lie ahead.

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