Rapid Extraction of Top-Quality Purified RNA
Extraction and purification of RNA is required for numerous downstream molecular biology applications such as RT-PCR, qPCR, Western blotting and RNA amplification.
Opinionated Science x Extraordinary Grace: Reacting to Bias in STEM
This episode of Opinionated Science is part of our latest podcast mini-series, where we are joined by esteemed STEM advocates, scientists as well as diversity, equity and inclusion experts who share their experiences interacting with and mentoring a virtual scientist named Grace. In this incredible episode, we speak with Sisters in Science who are taking social media by storm and helping to break stereotypes within STEM.
AI Tools Can Predict DNA Structure and Regulation
Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA’s regulatory elements and three-dimensional (3D) structure based solely on its raw sequence.
How a Mutated Eye Offers Insight into Cancer Development
Researchers have used a zebrafish eye mutation to study the role of a protein in preventing cell death, which could have implications for the development of cancer therapies
Next-Generation Sequencing Compared to Standard of Care Diagnostics
According to a study, next-generation sequencing diagnostic systems enable clinicians to simultaneously sequence multiple strands of DNA found in patient samples and use that analysis to identify a single pathogen.
3D Cell Culture: Will Organoids Add a New Dimension to Disease Modeling?
This article explores the world of organoids, their benefits and limitations, and where they may play a role in the future of disease modeling.
Developing Novel Cell Therapies by Rewiring T-Cell Genomes
In a recent Teach Me in 10 episode, Dr. Theo Roth discussed what targeted pooled knock-in screens are, how he is working to accelerate the discovery of cell-based therapies and how this process could reduce the time it takes to transition these therapies from the lab to the clinic.
An Introduction to Electroporation – A Tool for Transfection and Competent Cell Generation
There are many reasons you may want to deliver something into a cell, be it genetic material or a therapeutic drug, and electroporation is a vital tool to achieve this. In this article, we will consider what electroporation is, how it works and how it’s used.
How To Address NGS Challenges
Download this guide to learn how to select the appropriate NGS method and sequencing platform, deal with samples of variable quality, and set up and manage the data analysis pipeline.
Connecting Laboratories With Data-Driven Automation Software
Download this guide to learn more about automated software and the latest solutions available.
Sample Quality Control for Nucleic Acid Analysis Workflows
Sample QC can help maximize research success in both next-generation sequencing (NGS) and biobanking applications. Sample quality metrics such as nucleic acid size, integrity and concentration can be used to rank DNA and RNA fragments from 1 to 10.
Spatial Transcriptomics: Understanding Gene Regulation in the Tissue Context
Download this listicle to explore spatial transcriptomics applications and key technologies including next-generation sequencing based-methods, In situ sequencing-based methods and In situ hybridization-based methods.
Applications of Whole Exome Sequencing
Download this listicle to discover some key applications of whole exome sequencing such as identifying coding mutations in cancer, screening for mutations associated with disease and investigating alternative splicing events.