One Year on, Scientists Defend Canada’s Anti-Genetic Discrimination Law

Article

The Canadian Genetic Non-Discrimination Act (GNA), introduced last May, made it illegal to require individuals to disclose genetic test results or to compel individuals to undergo genetic tests for any agreement or service. However, a subsequent legal challenge has prompted a robust defense of the act from scientists in the May issue of the Canadian Medical Association Journal (CMAJ).

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Metagenomics: Exploring Microbiomes at Nature’s New Frontiers

Article

Advances in sequencing technologies are providing scientists with a powerful way to view microbial communities in unprecedented detail. Metagenomics is a rapidly evolving field that is uncovering a wealth of hidden biodiversity, revolutionizing our understanding of uncharted corners in the living world.

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10 Things We Didn't Know Last Week - 18 May 2018

List

The most exciting science new stories from the last 7 days

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Yeast Study Performs Hundreds of Simultaneous CRISPR Edits

Yeast Study Performs Hundreds of Simultaneous CRISPR Edits

News

A new technique which can alter hundreds of different genes at once in baker's yeast could greatly speed up CRISPR-Cas9 editing and offer a way to perform high-throughput functional genomics.

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SCRaMbLE Speeds Up Yeast Evolution
News

Scientists have created a new way of speeding up the genome evolution of baker’s yeast Saccharomyces cerevisiae. This is to develop a synthetic yeast strain that can be transformed on demand, making it industrial applications such as the mass production of advanced medicines to treat illnesses such as malaria and tuberculosis (TB).

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Artificial Cellular Compartments Built
News

How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich (TUM) and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.

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Stress Passed to Children Through Sperm RNA
News

Do your parents stress you out? Perhaps more than you think. A new study has suggested that, through alterations to genetic material in sperm, men who experience early-life stress may pass on physical and mental effects to their offspring.

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Tracking the Heritability of Cell Stress
Tracking the Heritability of Cell Stress
Article

As part of work recently published in Science Advances, a team of researchers from the Institute of Systems Biology at Yale University has built a microfluidic device to demonstrate that single cells preserve a memory of their mother's dynamic response to glucose limitation stress for multiple generations.

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The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
The 3D Structure of Telomerase: Uncovering Its Role in Human Disease
Article

Researchers have published the first detailed picture and description of the 3-dimensional molecular structure of telomerase – a discovery that could enable better targeted drug screening and could result in more successful telomerase-related clinical therapeutics.

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Phenotypic versus Target-based Screening for Drug Discovery
Phenotypic versus Target-based Screening for Drug Discovery
Article

Target-based screening has been the method of choice in drug discovery for the past two decades, but phenotypic screening is having something of a renaissance. We look at the advantages and applications of both.

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Study Shows Night Owls Have a 10% Higher Risk of Early Death
Study Shows Night Owls Have a 10% Higher Risk of Early Death
Article

Scientists study link between chronotype and death, and find night owls are at greater risk of health complications and earlier death.

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Why is a Molecule Necessary for Penile Erections Important for Brain Cell Communication?
Why is a Molecule Necessary for Penile Erections Important for Brain Cell Communication?
Article

New research sheds light on neuronal communication and adds more detail to the current picture of brain cell communication at the synapse, and the role of the messenger molecule nitric oxide.

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CRISPR Technology Could Revolutionize Animal Transgenics
CRISPR Technology Could Revolutionize Animal Transgenics
Article

Despite its role in advancing genetics research, transgenic modification of animal models is an aging and costly technique. A new tool that leverages CRISPR technology may make the entire process simpler and more efficient.

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