Clinical Microbial Identification by MALDI-TOF Mass Spectrometry

Article

Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) is a powerful analytical mass spectrometry technique that has generated numerous diagnostic and clinical applications, especially for the identification of microorganisms for medical diagnosis. Here we take a look at the role of MALDI-TOF in clinical microbial identification and what its future looks like.

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Sport Doping Screening in Biological Matrices by Multi-Dimensional LC-QToF

Poster

This work evaluated the performance of 2D LC variant using a QToF setup instead of a triple quadrupole mass spectrometer for the analysis of drug of abuse in urine targeting low and sub ppb level.

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Exploring Multiple Dimensions in the Forensics of “Space Candy” with Boston Uni. - Behind the Science

Video

In forensic toxicology laboratories, the accuracy and precision of an analytical technique are essential in determining what drugs or chemicals may have played a role in an individual's death. Is it possible to use one analytical technique to test a variety of different matrices - liquid or solid?

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X-ray Crystallography: Exploring the Frontiers of Structural Biology

Article

For over a century, X-ray crystallography has enabled scientists to elucidate biological structures in exquisite detail. Now, powerful new technologies are bringing unprecedented opportunities to add to the history of breakthroughs in this cutting-edge field.

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10 Things We Didn't Know Last Week - 13 July 2018

List

A round-up of the biggest science stories from this week.

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Enzyme Discovery Fuels War on TB

Enzyme Discovery Fuels War on TB

News

An enzyme structure discovery made by scientists could help to eradicate tuberculosis. They identified a weak point within this protein could be targeted to enable them to design specific molecules to block its function.

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Smart Solutions to Limit Greenhouse Gases
News

Researchers are looking into zero-emission greenhouses and clever ways of shaping livestock farming, land use and forest and nature management with the aim of cutting greenhouse gas emissions from agriculture and land use.

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Three-Cell Ignition Required
News

New research shows that NK-cell recruitment and activation requires a rather carefully choreographed interaction of three cell types in the headquarters of the slower adaptive immune-activation: the lymph node.

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Guardian of the Cell
News

Scientists unravel the structure, key features of a human immune-surveillance protein, setting the stage for more precise immune therapies.

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Strawberry’s Properties are More than Skin Deep
Strawberry’s Properties are More than Skin Deep
Article

Everyone loves a perfectly ripe strawberry, right? They count towards your five a day and contain important nutrients, vitamins and antioxidants. But what if science could help breeders make them even better?

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Where the Grass is Greener: Novel Solvents for the Environmentally Friendly Extraction of Phytocannabinoids
Where the Grass is Greener: Novel Solvents for the Environmentally Friendly Extraction of Phytocannabinoids
Article

As the demand for cannabis analysis grows researchers search for safer, greener solvents that are less damaging to human health and the environment.

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Enhancing Methods for the Chemical Characterization of Cannabis Products
Enhancing Methods for the Chemical Characterization of Cannabis Products
Article

Scientists, medical professionals, and consumers alike all stand to benefit from fully characterizing the chemical composition of cannabis.

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Revealing the Potential Risks of Cannabis Dabbing
Revealing the Potential Risks of Cannabis Dabbing
Article

A 2017 study on the chemistry of cannabis dabbing revealed potential side effects which may be a cause for concern given the popularity of this method of consumption.

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CO<sub>2</sub> Shortage Highlights that It’s Not Always the Bad Guy
CO2 Shortage Highlights that It’s Not Always the Bad Guy
Article

Say the words “carbon dioxide” to many people and often the first connotations that come to mind are negative things like emissions and global warming. Many governments around the globe are going to great lengths to reduce harmful emissions, including carbon dioxide (CO2), which remain worryingly high. However, believe it or not, a CO2 shortage is currently causing havoc in many areas of the food and beverage industry.

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Metabolomics: The Long Journey from Lab to Clinic
Metabolomics: The Long Journey from Lab to Clinic
Article

Recent improvements in technology are enabling the simultaneous detection and quantitation of large numbers of metabolites from biological samples. Here, we examine the challenges and innovations in metabolomics technologies and find out how these tools are impacting on clinical biomarker discovery.

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