A basic introduction to Dynamic Light Scattering (DLS)

Video

Dynamic Light Scattering (DLS) is a technique classically used for measuring the size of particles typically in the sub-micron region, dispersed in a liquid. The sensitivity of some modern systems is such that it can also now be used to measure the size of macromolecules in solution.

Watch Now

Mass Spectrometry: From Imaging to Metabolic Networks

Poster

We show that network analysis of co-localized ions from mass spectrometry imaging data provides a detailed chemo-spatial insight into the metabolic heterogeneity of tumor. Furthermore, module preservation analysis between colorectal cancer patients with and without metastatic recurrence suggests hypotheses on the nature of the different local metabolic pathways.

Read more

Providing Peace of Mind: Ultra Low-Level Detection of Pesticides in Baby Food

Blog

Pesticides are widely used to protect food crops from damage and consequently have the potential to end up in the food we eat. Young children and babies can be particularly susceptible to pesticide residues in food so testing for pesticide residues in food, and baby food in particular, is therefore critical for the preservation of human health.

Read more
Cryo-EM Reveals Interaction Between Major Drug Targets
Cryo-EM Reveals Interaction Between Major Drug Targets
News

For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects for conditions ranging from migraine to cancer.

Read more

Algorithm Helps Diagnose Zika Using Biomarkers
Algorithm Helps Diagnose Zika Using Biomarkers
News

A platform that can diagnose several diseases with a high degree of precision using metabolic markers found in patients’ blood has been developed by scientists at the University of Campinas (UNICAMP) in Brazil.

Read more

Bacterial Chaperone Structure Disentangled
Bacterial Chaperone Structure Disentangled
News

The structure of a protein called ClpB that helps to disentangle toxic aggregations like those found in Alzheimer's Disease has been visualized in unprecedented detail, giving information on exactly how ClpB tackles aggregated proteins

Read more

Sensor Detects Whiff of Bad Breath
Sensor Detects Whiff of Bad Breath
News

Ever wish you could do a quick “breath check” before an important meeting or a big date? Now researchers, reporting in ACS’ journal Analytical Chemistry, have developed a sensor that detects tiny amounts of hydrogen sulfide gas, the compound responsible for bad breath, in human exhalations.

Read more

Structure of Amino Acid Transporter Involved in Cancer Revealed
Structure of Amino Acid Transporter Involved in Cancer Revealed
News

The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. A team of University of Groningen scientists have used cryo-electron microscopy to elucidate the structure of the protein, which may generate leads for drug development.

Read more

Thermo Fisher Scientific Recognizes Tandem Mass Tag Grant Award Winners at ASMS 2018
Thermo Fisher Scientific Recognizes Tandem Mass Tag Grant Award Winners at ASMS 2018
News

International competition rewards four top proteomics researchers for outstanding innovation and impact.

Read more

 
 
 
Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells
Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells
Article

Although cisplatin is clinically proven to combat numerous human cancers – bladder, head and neck, lung, ovarian, testicular – resistance to treatment remains a key challenge, and cisplatin patients can often relapse. Having the ability to determine the cellular uptake of cisplatin is key to developing novel strategies to increase tumor cell sensitivity to cisplatin.

Read more

Case Study: Improve your lab’s efficiency and data compliance with a chromatography data system
Case Study: Improve your lab’s efficiency and data compliance with a chromatography data system
Article

In this Case Study, Peter Zipfell of Thermo Fisher Scientific explains how Broughton Laboratories, an analytical laboratory that supports method development and validation projects across pharma, implemented and upgraded a chromatography data system (CDS), increasing lab efficiency and improving data verification processes for overall time savings.

Read more

The Ionic Basis for Electrosensation In Sharks and Skates
The Ionic Basis for Electrosensation In Sharks and Skates
Article

Neuroscientists have identified the ionic basis for electroreception in sharks and their relatives, skates.

Read more

Cryo-EM and CX-MS: The Power Couple of Proteomics
Cryo-EM and CX-MS: The Power Couple of Proteomics
Article

An ambitious new workflow has married two cutting-edge proteomic analysis techniques to improve imaging of large protein assemblies. The combination of electron cryo-microscopy (cryo-EM) and cross-linking coupled mass spectrometry (CX-MS) allows deeper interrogation of protein structures to a level of detail that the techniques are incapable of obtaining on their own.

Read more

How to Tell “Fake” Olive Oils from the Genuine Article
How to Tell “Fake” Olive Oils from the Genuine Article
Article

With olive oil’s popularity on the increase in recent years, olive oil production and sales have become big business. However, it also opens the industry up to fraudsters looking to profiteer from this trend. To tackle this problem, scientists have been exploiting differences at the chemical level to expose adulterated products.

Read more

Mass Spectrometry in Biopharmaceutical Discovery
Mass Spectrometry in Biopharmaceutical Discovery
Article

Biotherapeutics now makes up 25% of new drugs approvals. Their efficacy and safety are highly dependent on their structures, which are complex, heterogeneous and subject to modification. Advances in mass spectrometry are allowing more information on higher order structure and new imaging techniques are even providing insights into how biological drugs behave in vivo.

Read more

 
 
 

We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy