Beautiful 3-D Reconstructions of Brain Cells and All Their Synapses

Video

Prof Jeff Lichtman describes his group's work to map the brain from the synapses up.

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Behind the Science, S2 Ep 10: Kari Organtini on options for analyzing pesticides with GC-MS/MS

Video

Senior scientist Kari Organtini shows Jen Fournier an increasingly popular technology that uses GC-MS/MS at atmospheric pressure - or APGC - and is available as a simple source change for a triple quadrupole mass spectrometer so the MS can be used with either GC or LC.

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The War on Plastics: Is It Too Little Too Late?

Article

With UK Prime Minister Theresa May announcing today that UK supermarkets must have a plastic free aisle as part of her government’s 25-year environmental improvement plan, it is the latest in a line of reforms seeking to reduce the harmful plastic contamination that has become a worldwide scourge.

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4 Challenges in Proteome Analysis

List

Proteomics is a rapidly expanding field, aided by improvements in instrumentation accuracy and sensitivity, size and affordability. Whilst it is a valuable tool in the quest for improved understanding, diagnosis and treatment, a number of areas are proving problematic. In this list, we will discuss some of the challenges that researchers come up against in proteome analysis.

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New Crystal Structure of (Ph)PINK1 Aids Understanding of Early Onset Parkinson’s

Article

Scientists have determined the crystal structure of PhPINK1 bound to it's substrate ubiquitin. Mutations of PINK1 are associated with early onset Parkinson's disease and it is expected that this information will help the design of Parkinson's therapeutics.

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Longevity Protein Reveals its Secrets

Longevity Protein Reveals its Secrets

News

In a recent study, researchers revealed the three-dimensional structure of a proteins linked to longevity and metabolism, beta-Klotho, illuminating its intricate mechanism and therapeutic potential. The study findings could have implications for therapies developed to treat a wide range of medical conditions, including diabetes, obesity, and certain cancers.

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"Buck-Naked" Barley Gets New Lease of Life
News

Researchers are giving an ancient grain a new life: this barley is naked, but not in an indecent way.

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All in a Droplet: Atomic Resolution of ALS Protein Resolved
News

Researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone.

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Meteorite Dust Charts History of the Solar System
News

Using a state-of-the-art mass spectrometer to measure the titanium isotopes in supernova SiC grains, scientists have been able to test theoretical calculations about the origins of the solar system.

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