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Research-grade Q-TOF LCMS-9030

Video

Shimadzu’s research-grade LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer combines the engineering DNA from our proven triple quadrupole (LC-MS/MS) platform with powerful, new TOF architecture to transform high mass accuracy workflows.

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Metabolomics, She Wrote: Towards Accurate Time of Death Analysis by GC-MS

Article

Estimating the time of death is one of the most important and challenging tasks in a forensic investigation. Therefore a laboratory method based on a robust biomarker would help to improve the reliability of time of death analysis.

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The Agricultural Perspective on Water Contamination by Pharmaceuticals

Article

Despite centuries of research into drug development, investigation into the environmental impact of pharmaceuticals is a much younger field. If not treated effectively, there is the potential for pharmaceuticals in wastewater to affect the agricultural industry through the use of this contaminated water supply.

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Delivering Assurance and Credibility: Using Modern Software Systems to Ensure Compliance

Infographic

With computerized laboratory systems now taking the place of paper systems, your compliance strategy must adapt, or you risk difficult regulatory inspections.

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Analysis Settles a Volcanic Debate

Analysis Settles a Volcanic Debate

News

Research uses tree rings to shed light on discrepancies between archeological and radiocarbon evidence in dating the ancient volcanic eruption of Thera.

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Scientists Discover Intricacies of Serotonin Receptor Crucial for Better Drugs
News

Researchers have figured out precisely why one drug binds to the serotonin receptor 5-HT2BR and activates it to cause heart problems while very similar drugs do not. They've also discovered why a third drug acts like a 5-HT2BR antagonist - it blocks the receptor's activity - while the very well-known similar hallucinogenic drug LSD does not.

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Progress toward Plugging an Antibiotic Pump
News

Each year in the U.S., at least 23,000 people die from infections caused by antibiotic resistant bacteria. Using computer modeling, researchers are developing the means to prevent some of those deaths. One way bacteria develop resistance is by producing pumps that spit out antibiotics, before they can do any damage. The researchers teased out the details of how one antibiotic pump works.

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Why Do Some Microbes Live in Your Gut While Others Don’t?
News

Researchers have found a new approach to identifying the genes that may be important to help microbes live successfully in the human gut.

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UHPLC- Robust Technology Built to Perform
UHPLC- Robust Technology Built to Perform
Article

Chromatography is the backbone of analytical laboratories with high performance liquid chromatography (HPLC) representing the largest portion. Classical HPLC has been challenged - or complemented - in the last decade by ultrahigh performance liquid chromatography (UHPLC).

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Team Work Helps Overcome Environmental Challenges
Team Work Helps Overcome Environmental Challenges
Article

We spoke to Andrew Howley from Adventure Scientists,a pioneering not-for-profit organization that seeks to unite skilled adventurers with scientists keen to receive valuable data from remote areas, to learn more about the initiative and the impact their projects are having in the scientific community and beyond.

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What’s in a Wine Name?
What’s in a Wine Name?
Article

There’s nothing like a nice cool glass of rosé on a balmy summers evening. Whether you’re an adventurous type who likes to try a new wine every time or you have your go-to favourites, you put your trust in producers and retailers to deliver the products that they claim to be – but are they?

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One-Way vs Two-Way ANOVA: Differences, Assumptions and Hypotheses
One-Way vs Two-Way ANOVA: Differences, Assumptions and Hypotheses
Article

A key statistical test in research fields including biology, economics and psychology, Analysis of Variance (ANOVA) is very useful for analyzing datasets. It allows comparisons to be made between three or more groups of data. Here, we summarize the key differences between these two tests, including the assumptions and hypotheses that must be made about each type of test.

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3 Recent Developments in Toxicity Testing
3 Recent Developments in Toxicity Testing
Article

The early toxicity testing market is witnessing a robust growth in recent years. Here we take a look at some of the recent developments that are playing important roles in this process.

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From Metabolite to Biomarker: Mass Spectrometry in Diagnostics
From Metabolite to Biomarker: Mass Spectrometry in Diagnostics
Article

Professor Alain van Gool, Professor of Personalized Healthcare at Radboud University Medical Center (Radboudumc), in Nijmegen, The Netherlands, helps oversee Radboudumc’s 19 Technology Centers, which span multiple aspects of biomedical science. He also has a rather more specialized position as head of the Translational Metabolic Laboratory (TML).

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