New Crystal Structure of (Ph)PINK1 Aids Understanding of Early Onset Parkinson’s

Article

Scientists have determined the crystal structure of PhPINK1 bound to it's substrate ubiquitin. Mutations of PINK1 are associated with early onset Parkinson's disease and it is expected that this information will help the design of Parkinson's therapeutics.

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4 Challenges in Proteome Analysis

List

Proteomics is a rapidly expanding field, aided by improvements in instrumentation accuracy and sensitivity, size and affordability. Whilst it is a valuable tool in the quest for improved understanding, diagnosis and treatment, a number of areas are proving problematic. In this list, we will discuss some of the challenges that researchers come up against in proteome analysis.

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Beautiful 3-D Reconstructions of Brain Cells and All Their Synapses

Video

Prof Jeff Lichtman describes his group's work to map the brain from the synapses up.

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The War on Plastics: Is It Too Little Too Late?

Article

With UK Prime Minister Theresa May announcing today that UK supermarkets must have a plastic free aisle as part of her government’s 25-year environmental improvement plan, it is the latest in a line of reforms seeking to reduce the harmful plastic contamination that has become a worldwide scourge.

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Multi-Analyte Mass Spectrometry Software for Faster Quantitative Analysis and Higher Productivity

Video

Shimadzu's LabSolutions Insight Software for LC-MS/MS and GC/MS provides powerful data mining and analytics capabilities.

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First Global Atlas of Soil Bacteria

First Global Atlas of Soil Bacteria

News

What lives in your dirt? Researchers are one step closer to finding out after compiling the first global atlas of soil bacterial communities and identifying a group of around 500 key species that are both common and abundant worldwide.

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"Buck-Naked" Barley Gets New Lease of Life
News

Researchers are giving an ancient grain a new life: this barley is naked, but not in an indecent way.

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All in a Droplet: Atomic Resolution of ALS Protein Resolved
News

Researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone.

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Meteorite Dust Charts History of the Solar System
News

Using a state-of-the-art mass spectrometer to measure the titanium isotopes in supernova SiC grains, scientists have been able to test theoretical calculations about the origins of the solar system.

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