Application Notes

 
Turn Subtle Phenotypic Responses into Robust Discoveries
Application Note

Today’s drug discovery strategies require candidate compounds to fail early and cheaply in the discovery stage, rather than late and expensively in the clinical phase. Testing compounds in physiologically relevant model systems and leveraging information from image-based screens are ways to focus on those compounds that give rise to the right phenotypic changes without undesirable effects on the system.

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PCR for early diagnosis of Invasive Aspergillosis
Application Note

In this case study, Dr. Lewis White and Prof. Rosemary Barnes of the Regional Mycology Reference Laboratory, Cardiff, discuss how patient outcomes can be improved by introducing Aspergillus PCR.

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Direct Analysis of Polar Pesticides Without Derivatization
Application Note

This ion chromatographic approach to the analysis of polar pesticides offers the ability to include multiple analytes in a single injection without derivatization.

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Rapid Development of a 9 component Multivariate Calibration for the analysis of Metabolites in Chemically Defined Cell Culture Media
Application Note

This study assessed the performance of the HyperFlux™ PRO Plus Raman Spectroscopy System (Tornado Spectral Systems) for the quantitative analysis of biochemical components in a simplified chemically defined pseudo growth medium for mammalian cell culture.

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Measuring Highly Concentrated Biologics
Application Note

Lunatic accurately measures highly concentrated biologics in a dilution-free, accurate and high-throughput way.

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Screen for 664 Forensic Drugs in Under 10 Minutes [Toolkit]
Application Note

With this vMethod, accurate testing of 664 forensic drugs in less than 10 minutes is now a reality.

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The Impact of Electrode Particle Size and Shape on Battery Slurry Viscosity
Application Note

Using Morphologi G3 to monitor and control the electrode particle characteristics and viscosity of battery slurries.

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Concentration Limits for Zeta Potential Measurements in the Zetasizer Nano
Application Note

Explains the concentration limits for successful zeta potential measurements to be made. A case study is used to illustrate the limits of concentration and describes what happens to the quality of data if the sample concent.

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Sample Prep: The Forgotten Dimension in HPLC
Application Note

Although often forgotten, sample preparation is the most important factor in achieving reproducibility from even the most advanced chromatographic methods. In this paper, you can learn about some ways that sample preparation can affect the selectivity, sensitivity and reproducibility of an analysis.

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Molecular and Bulk Characterization of PLA and PLGA Samples Using Multi-Detector GPC and Rheometry
Application Note

Exploring the relationship between molecular characteristics and bulk rheological properties of biodegradable polymers.

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