Latest Application Notes
Comprehending COVID-19: Peptide Mapping of the SARS-CoV-2 Spike Protein
The SARS-CoV-2 spike protein has rightly garnered attention as a leading candidate for protein-based vaccines for COVID-19. Multiple studies have shown that neutralizing antibodies bind to the spike protein at both peptide and peptidoglycan epitopes.
Rapid and Sensitive Label-Free Proteome Quantification
Untargeted proteome-wide quantification is the most commonly used strategy in proteomics. Data dependent and now increasingly data-independent acquisition strategies are used for routine quantification of samples from cell lines, tissues and for affinity-based interaction proteomics.
Monitoring T-Cell Exhaustion and Effects of Immunotherapy
The efficient monitoring of T-cell surface markers, cytokines and expression patterns is critical to the study of further immunotherapies. Download this app note to discover how cell analyzers can help.
The Analysis of Pharmaceuticals Using Dual Injection (U)HPLC
Many people pursue ideas of “efficiency” as an ideal for daily life — ideas include how many tasks we can accomplish in a short time frame and how we can minimize our impact on the environment. The same can be true with high performance liquid chromatography (HPLC).
Sample Quality Control in Next-Generation Sequencing Workflows
Next-generation sequencing (NGS) is an essential tool in molecular biology laboratories for the analysis of nucleic acid samples in numerous basic, translational and clinical research settings. Download this app compendium to discover systems that can be used to analyze genomic DNA, cell-free DNA, total RNA.
Highly Sensitive Methylation Detection
DNA methylation plays an important role in cell growth by regulating gene expression. Download this tech note to discover a solution that enables highly sensitive methylation detection, reduces hands-on time and is suitable for a wide variety of research.
MTT Cell Proliferation, Viability and Cytotoxicity Assay
The MTT cell proliferation assay is a commonly used colorimetric assay for assessing cellular metabolic activity. Download this app note to discover how using a pipetting robot with this assay can reduce time and costs and allow processing of different plate formats.
Nucleic Acid Analysis for Sample Quality Assessment
Download this application compendium to discover analyzer systems that eliminate common QC bottlenecks, improve lab efficiency and deliver reliable and accurate nucleic acid sample assessment.
Quality Control of Genomic DNA for The French Kidney Disease Study
Biobanks play a crucial role in medical research, providing users with well-characterized and professionally annotated collections of biospecimens. Download this app note to discover a system that provides DNA integrity numbers to aid QC and reliable evaluation of gDNA integrity.
Rapid MS/MS Analysis With Acoustic Ejection Mass Spectrometry
Download this app note to discover a system that provides high-speed and reproducible quantification, has broad compound coverage and is purpose built for incorporation into high-throughput screening workflows.