Latest App Notes & Case Studies
App Note / Case Study
Your Guide to Multiple Attribute Methodology (MAM)
In biotherapeutic process development, evaluating and tracking potential product quality attributes (PQAs) is crucial to ensure quality, safety, and efficacy.
App Note / Case Study
Analysis of Common Preservatives in Personal Care Products by HPLC With UV Detection
Parabens refer to a group of p-hydroxybenzoic acid esters that are widely used as antimicrobial preservatives in many everyday products due to their broad spectrum of activity as well as their chemical and thermal stability.
App Note / Case Study
Dioxin and Persistent Organic Pollutants Analysis
Dioxins and other persistent organic pollutants (POPs) are everywhere, from the environment to our food. Environmental threats continue to evolve and laboratories need to analyze samples to maintain food quality and safety while guarantying their results are compliant with regulations and controls.
App Note / Case Study
Analysis of Genotoxic Nitrosamines in Losartan
Download this app note to discover a system that demonstrates good chromatographic separation of nitrosamine compounds and provides enhanced sensitivity.
App Note / Case Study
Shotgun Proteomics for Unbiased Quantification
Shotgun proteomics has the capacity to deliver in-depth information on the identification, the relative amount, and the modification patterns of ever larger fraction of the proteins present in a sample. This has made it an essential approach in most biological research areas.
App Note / Case Study
Greater Precision for Transformative Drug Discovery
Target identification and characterization are key challenges in drug discovery and begin with identifying the function of a possible therapeutic target and its role in the disease.
App Note / Case Study
Comprehending COVID-19: Peptide Mapping of the SARS-CoV-2 Spike Protein
The SARS-CoV-2 spike protein has rightly garnered attention as a leading candidate for protein-based vaccines for COVID-19. Multiple studies have shown that neutralizing antibodies bind to the spike protein at both peptide and peptidoglycan epitopes.
App Note / Case Study
Ultra-High Sensitivity Proteomics
Untargeted proteome-wide quantification is the most commonly used strategy in proteomics. Data dependent and now increasingly data-independent acquisition strategies are used for routine quantification of samples from cell lines, tissues and for affinity-based interaction proteomics.
App Note / Case Study
Monitoring T-Cell Exhaustion and Effects of Immunotherapy
The efficient monitoring of T-cell surface markers, cytokines and expression patterns is critical to the study of further immunotherapies. Download this app note to discover how cell analyzers can help.
App Note / Case Study
The Analysis of Pharmaceuticals Using Dual Injection (U)HPLC
Many people pursue ideas of “efficiency” as an ideal for daily life — ideas include how many tasks we can accomplish in a short time frame and how we can minimize our impact on the environment. The same can be true with high performance liquid chromatography (HPLC).
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