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A Novel, Highly Selective Phosphopeptide Enrichment for Identification and Localization

Phosphopeptide enrichment is one of the most challenging sample preparation steps for LC/MS analysis due to the variation in reproducibility and selectivity caused by manual sample preparation.

The LC/MS analysis of the resulting phosphopeptide samples can be made difficult, due to factors such as suppression of phosphopeptide peaks and reduced ionization efficiency.

In this app note, discover a workflow solution for phosphopeptide enrichment that is:

  • Fully automated
  • Highly selective
  • Reproducible