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Enhancing Target Capture Techniques in Long-Read Sequencing

Digital screen with glowing DNA strands and sequencing ATGC data background.
Credit: iStock

Long-read sequencing technology has enabled researchers to address complex genomics regions, resolve structural variations and gain valuable insights into diseases and biological processes.

However, challenges remain in achieving efficient and cost-effective analysis, particularly when targeting specific genes or regions of interest. To overcome these limitations, innovative target capture techniques have been developed, allowing for improved enrichment of long-read libraries.

This application note explores these advancements, showcasing how optimized workflows can enhance sequencing performance and provide deeper insights into genomic complexities, particularly in cancer research and other applications.

Download this application note to discover: 

  • The advantages of enhanced target enrichment for genomic analysis
  • Insights into overcoming challenges associated with sequencing difficult regions
  • Strategies to improve cost-effectiveness and efficiency in research applications
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