High Utilization and Robustness of the Alliance™ iS HPLC System Using the Analysis of a USP Impurity Method

In many regulated laboratories, there is a need for reliable, robust High Performance Liquid Chromatography (HPLC) systems to accommodate the demand for high instrument utilization and product timelines. With these types of restraints, regulated laboratories need an HPLC system capable of operating for extended periods of time with minimal downtime. The high utilization of the HPLC system must also produce high-quality, reliable results. The Alliance iS HPLC System is a streamlined system with features that help to reduce human error in system operation, thereby decreasing the need to rerun analyses. One example of a feature on the Alliance iS HPLC System is the modernized interface that enhances the ease of use by HPLC users to maximize the system’s uptime and efficiency. In this application note, the Alliance iS HPLC System ran for a time period of forty days with consistent, accurate results of the USP Fluconazole Organic Impurities method.
Over the course of the study, a system suitability solution and a Fluconazole sample containing impurities were monitored each day to assess system suitability.