Elemental impurities in pharmaceutical formulations can interfere with drug efficacy or have a toxic effect on the patient. Regulators have issued guidelines—such as ICH Q3D, USP 232 and USP 233 Elemental Impurities.

Download this application compendium to learn how to monitor a range of metal elemental impurities in pharmaceutical materials using elemental analysis techniques such as:

• ICP-OES
• ICP-MS or,
• AAS

As well as tips to ensure specific validation requirements described in the guidelines are met.