We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
Purity – The Nucleo (TIDES) for your Success
Application Note

Purity – The Nucleo (TIDES) for your Success

Purity – The Nucleo (TIDES) for your Success
Application Note

Purity – The Nucleo (TIDES) for your Success

The purity of oligonucleotide preparations produced by solid-phase synthesis can be very high. However, purification is often required to remove incomplete or erroneous sequences.

Anion exchange chromatography (AIEX) is an attractive choice since it can separate the negatively charged oligonucleotides based on length. The obtained purity and yield of the full-length oligonucleotide is dependent on the chromatographic resolution as well as the binding and elution conditions.

Comparing WorkBeads™ 40Q with one of the market leading resins proved:
- Better resolution
- Higher purity
- Higher yield
Advertisement