Latest Articles
4 Considerations for Creating Standardized Cannabis Extracts
ArticleDosing and labeling are currently big issues for cannabis consumers and these results could help improve the quality and consistency of cannabis extracts.
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Cisplatin Efficacy: The Importance of Measuring Uptake in Cancer Cells
ArticleAlthough cisplatin is clinically proven to combat numerous human cancers – bladder, head and neck, lung, ovarian, testicular – resistance to treatment remains a key challenge, and cisplatin patients can often relapse. Having the ability to determine the cellular uptake of cisplatin is key to developing novel strategies to increase tumor cell sensitivity to cisplatin.
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Case Study: Improve your lab’s efficiency and data compliance with a chromatography data system
ArticleIn this Case Study, Peter Zipfell of Thermo Fisher Scientific explains how Broughton Laboratories, an analytical laboratory that supports method development and validation projects across pharma, implemented and upgraded a chromatography data system (CDS), increasing lab efficiency and improving data verification processes for overall time savings.
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The Ionic Basis for Electrosensation In Sharks and Skates
ArticleNeuroscientists have identified the ionic basis for electroreception in sharks and their relatives, skates.
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Cryo-EM and CX-MS: The Power Couple of Proteomics
ArticleAn ambitious new workflow has married two cutting-edge proteomic analysis techniques to improve imaging of large protein assemblies. The combination of electron cryo-microscopy (cryo-EM) and cross-linking coupled mass spectrometry (CX-MS) allows deeper interrogation of protein structures to a level of detail that the techniques are incapable of obtaining on their own.
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Mass Spectrometry in Biopharmaceutical Discovery
ArticleBiotherapeutics now makes up 25% of new drugs approvals. Their efficacy and safety are highly dependent on their structures, which are complex, heterogeneous and subject to modification. Advances in mass spectrometry are allowing more information on higher order structure and new imaging techniques are even providing insights into how biological drugs behave in vivo.
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How to Tell “Fake” Olive Oils from the Genuine Article
ArticleWith olive oil’s popularity on the increase in recent years, olive oil production and sales have become big business. However, it also opens the industry up to fraudsters looking to profiteer from this trend. To tackle this problem, scientists have been exploiting differences at the chemical level to expose adulterated products.
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Bringing Trusted Techniques and Technology to the Cannabis Testing Lab
ArticleTranslating from fields like food and pharma to the cannabis testing sector is helping to provide medical patients and recreational consumers with safe thoroughly tested cannabis.
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How Mass Spectrometry Has Changed the Cancer Diagnostics Game
ArticleAlthough histopathology is still the gold standard for diagnosing cancer, molecular analysis using MS has gained traction in recent years for detecting tumors, monitoring progression, and even predicting treatment response.
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Advances in Fragment-Based Drug Discovery
ArticleOver the past decade, fragment-based drug discovery has garnered increasing interest among drug discovery experts and has established itself as a key approach within the field – acting as an alternative starting point for the discovery of high-quality lead candidates. This article discusses the evolution of FBDD, highlights key drug discoveries, and explores the advantages and challenges of harnessing this approach
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