Re-Engineer Gas Chromatography Where It Matters Most

CLARUS® NOVA GC Reliable Gas Chromatography Workflows for Every Lab Next Generation Clarus Designed for Efficiency & Sustainability Energy Efficient Architecture Smart Carrier Gas Management Clarus Nova GC builds on decades of PerkinElmer GC Innovation to deliver reliable performance, fast analysis, and the flexibility modern laboratories demand. Designed for laboratories across petrochemical, pharmaceutical, food safety, and environmental testing, the Clarus Nova GC provides accurate, reproducible results that keep workflows moving and decisions on track. Optimized system design reduces energy consumption and other operational costs. Lower consumption and operating costs by leveraging hydrogen carrier gas safety and reduced carrier gas flow during standby. Built for Modern Laboratories High-Speed Performance Faster separations and increased sample throughput. Flexible Software Integration Compatible with SimplicityChrom™ and leading CDS platforms. Configurable Platform Expanded capabilities as your laboratories evolve. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTSAFETY YOU CAN TRUST Engineered safeguards for reliable laboratory operation. Clarus Nova GC integrates real time monitoring, automated protection mechanisms, and built in diagnostics to ensure safe operation in laboratories running demanding GC workflows. Designed to support hydrogen carrier gas and high throughput operation, the system helps laboratories operate confidently while minimizing risk. Integrated Hydrogen Sensor Leak Detection and Alerts Emergency Shutdown Protection Secure Gas Handling Continuously monitors hydrogen levels and triggers alerts/shutdown above safety threshold levels. Built in diagnostics identify gas leaks early and notify operators to prevent hazardous situations. Automatically shuts down the instrument when abnormal operating conditions are detected. Supports approved regulators, inline filters, and optional hydrogen snubbers for safe gas management. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTRE-ENGINEERED TO KEEP YOUR LAB RUNNING Clarus Nova GC combines intelligent monitoring, predictive maintenance, and streamlined workflows to help laboratories maintain uptime and deliver consistent results. Start Runs with Confidence Automated leak checks and pressure sensors enable precise gas flow controls for separation giving confidence in results for every run. Stay Ahead of Maintenance Track consumables and service needs with predictive alerts. Simplify Routine Service Tool-free maintenance, in-built oven LED lamp and quick consumable changes reduce downtime and allows for hassle-free servicing. Detect Issues Early Re-engineered Clarus Nova GC Platform Benefits Stable Performance Smart gas controls and precise oven temperature control performance maintain consistent results. Real time system monitoring and audio/visual indicators help you address issues in real time. Keep Workflows Moving Continuous operations with Hot swap autosampler towers and CDS connectivity. Connected Workflows SimplicityChrom™ integration and remote instrument visibility streamline laboratory operations. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE APPLICATIONS SUPPORT CONTACT Efficient Operation Support for alternative carrier gases and energy efficient system architecture help reduce operating costs.AND THERE’S MORE… Configured Flexibility Adaptable configurations for evolving methods and applications. Detectors FID (Flame Ionization Detector) Gold standard for hydrocarbons, high sensitivity, wide dynamic range. Now available with a Methanizer. TCD (Thermal Conductivity Detector) NEW Reliable, universal, for permanent gas analysis for petrochemical and environmental workflows. ECD (Electron Capture Detector) Ideal for halogenated compounds and pesticide residue analysis in food safety. MS 2400™ SQ Mass Spectrometer Seamless GC-MS integration for structural confirmation and trace-level sensitivity. Dual Simultaneous Injection Double your throughput, two samples, one run. AS 2400™ Liquid Autosampler Hot-swap towers for uninterrupted sample processing. SWAFER™ Technology Effortless multi-dimensional GC for complex separations. SimplicityChrom™ CDS Intuitive workflows, smart alerts, and clear visualizations. Hydrogen Carrier Gas Enabling monitoring leaks and safety. High-Speed GC Oven Faster heat-up and cool-down for shorter Energy-Efficient Design Lower power consumption and support for alternative carrier gases. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY HS 2400™ M Headspace Autosampler Pressure balanced technology – minimal to zero carryover & precise analysis. External Valve Oven NEW 1. Natural Gas Analyzer 2. Transformer Oil Gas Analyzer Injectors Packed: Accommodates on-column to wider bore capillary columns, programmed flow/pressure support 4 gas types. Split/Splitless: Supports high split ratios, 6 software configurable gas handling and 4 gas types. Programmable Split/Splitless: Temperature programmable injector with oven tracking mode and supports large SOFTWARE APPLICATIONS SUPPORT CONTACT cycle times. volume injection (50uL) with autosampler.ADVANCED POWER. ADAPTIVE SOLUTIONS. The Clarus Nova GC is designed to grow with your lab, integrating seamlessly with advanced technologies that expand capability, increase throughput, and simplify workflows. MS 2400™ SQ Mass Spectrometer Advanced GC-MS coupling • Trace-Level Sensitivity: Confident detection of low-level compounds. • Expanded Analysis: Seamless GC-MS coupling for demanding samples. • Reliable Performance: Precision for complex workflows. HS 2400™ M Headspace Autosampler Maximum Efficiency and reliability • Pressure-balanced design for consistent results. • Minimal Carryover: Maximum reliability for high-throughput labs. • Flexible Sample Compatibility: Supports 10, 20, and 22 mL vials (crimp or screw caps). SimplicityChrom™ CDS Smarter Software for Smarter Labs with improved stability • Intuitive Workflows: Reduce training time and errors. • Smart Notifications: Streamline troubleshooting and operation. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE APPLICATIONS SUPPORT CONTACT • Clear Visualizations: Accelerate data interpretation.ADVANCED POWER. ADAPTIVE SOLUTIONS. Clarus Nova GC expands its gas analysis capabilities with new solutions for Thermal Conductivity Detection (TCD), Natural Gas Analysis (NGA), and Transformer Oil Gas Analysis (TOGA). These configurations enable laboratories to perform critical gas measurements across petrochemical, energy, and industrial applications using proven GC technology. Thermal Conductivity Detector (TCD) Universal Multi-Gas Analysis Natural Gas Analysis (NGA) Comprehensive Natural GC Solution Transformer Oil Gas Analysis (TOGA) Prevent Transformer Failures Key Features • Proven 4 filament Wheatstone bridge detector design • Automatic electronic balancing for stable baselines • Dedicated reference and sample gas channels • Supports up to three TCD detectors Applications • Petrochemical Analysis • Biogas Monitoring • Permanent Gas Analysis • Green Energy And Environmental Monitoring Key Features • Multi-Channel GC System: 3 detector system (TCD/TCD/FID) run simultaneously. • Fast, Accurate Results: Complete analysis in 15–30 mins with high sensitivity. • Standards-Compliant: Meets standard method requirement (ASTM, GPA, ISO etc). Automated Diablo EZ reporter plug in for NGA reporting needs. Applications • Natural Gas Analysis • Refinery Gas Monitoring • Industrial Gas Testing Key Features • ASTM D-3612-02 Method C Compliant: Industry-standard method for analyzing headspace gases from transformer oil. • Fast and Accurate GC Analysis: Automated analysis with HS 2400™ M Headspace Sampler. • Multi-Gas Detection: TCD and FID with Methanizer for complete quantification of dissolved gases in transformer oil. Applications • Transformer Condition Monitoring • Dissolved Gas Analysis INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE APPLICATIONS SUPPORT CONTACT • Electrical Asset DiagnosticsINNOVATIONS THAT KEEP YOU AHEAD Dual Simultaneous Injection (DSI) Double Your Productivity The Clarus Nova GC incorporates Dual Simultaneous Injection, a breakthrough for high-throughput labs. Two Samples, One Run: Inject and analyze two samples at the same time, ideal for busy workflows that demand high turnover. Faster Turnaround: Cut sample analysis time in half without compromising accuracy or reproducibility, enabling faster QA/QC results. Greater Automation and Convenience: Dedicated sampling towers for each injector, supporting fully automated workflows with minimal manual intervention. Cost Efficiency: Maximize instrument utilization and reduce per-sample operating costs. Perfect for High-Demand Labs: Food safety, petrochemical, and environmental testing benefit from accelerated throughput. SWAFER™ Technology Multi-Dimensional GC Made Simple Complex samples demand advanced separation power. SWAFER delivers multi-dimensional GC without the complexity. Seamless Column Switching: Switch between columns automatically for enhanced resolution of challenging matrices. No Complex Plumbing: Simplifies setup with full software control of the configuration, no manual valve configurations or re-plumbing required. Expand Analytical Capability: Resolve co-eluting compounds and improve confidence in results for petrochemical and environmental applications. Future-Ready: Adaptable for emerging methods and regulatory requirements. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE APPLICATIONS SUPPORT CONTACTSIMPLICITYCHROM™ SOFTWARE Intuitive Control for Modern GC SimplicityChrom™ simplifies GC operation with an intuitive interface, automated workflows, and secure data management that help laboratories run samples faster while reducing training time. Simplicity Vision™ enables remote instrument monitoring. Designed for Simplicity Intuitive Interface Clean, streamlined interface that shortens training time and improves productivity with customizable interface Enhanced Stability Improved robustness and software stability ensure reliable operation across routine and advanced GC applications. to suit different needs of a workflow. Expanded Application Support Supports multiple workflows using GC detectors (TCDNEW), Mass Spec, External Valve ovens (NGA/TOGA), and Headspace sampler. One software controls GC, HS and GCMS in one platform. Flexible CDS Integration Compatible drivers allow Clarus® Nova GC to integrate Automated NGA Integration Automated TXO file implementation integrated with Diablo EZ reporter for NGA reporting. Secure Data Handling Database driven architecture with Integrated audit trails and electronics signatured support regulatory compliance including 21 CFR Part 11. Windows 11 Ready Upgraded operating system without disrupting lab operations. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE APPLICATIONS SUPPORT CONTACT with 3rd party chromatography data systems.REAL SOLUTIONS. REAL WORLD TESTING. Industrial • FOIL and GOIL analysis for refinery and petrochemical streams. • Reliable permanent gas detection with TCD. • NGA and TOGA capabilities for gas and transformer oil testing. Food • High-throughput headspace analysis with hot-swap towers. • Fewer reruns with proactive diagnostics. • Configurable design for evolving food safety methods. Pharmaceutical • Audit-ready logs and system suitability checks. • Consistent method transfer across global sites. • Predictive alerts for uninterrupted workflows. Environmental • Rapid VOC and pollutant detection with high-speed oven. • Reliable permanent gas monitoring for compliance INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE APPLICATIONS SUPPORT CONTACT • Energy-efficient design and alternative carrier gas support.INDUSTRIAL KEY MARKETS Petrochemical and Refinery Gas Analysis Petrochemical and refinery laboratories rely on gas chromatography to monitor permanent gases and hydrocarbon streams across production and processing operations. Accurate analysis supports product quality, process control, and regulatory compliance. The Clarus Nova GC platform supports NGA, TOGA, refinery gas, and permanent gas workflows. Integrated TCD detection and automated operation enable reliable results in continuous industrial environments. Petrochemical Lab Benefits and Safety: • Permanent gas detection using TCD for reliable industrial gas analysis • Application ready NGA and TOGA workflows for natural gas and transformer oil testing • Continuous monitoring with automated diagnostics to reduce interruptions • High throughput analysis for refinery and petrochemical laboratories • Stable operation for demanding industrial environments Arnel Configurable GC Solutions: Advanced GC solutions tailored for complex gas characterization and refinery gas analysis. Designed for demanding environments, Arnel systems deliver reliable, repeatable results while simplifying operation and maintenance. • Configurable systems for refinery gas and complex hydrocarbon analysis • Reliable, repeatable performance in lab or field environments • Flexible design for simplified maintenance and customization INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTNGA Standard Test Mix with 3 channel detection (FID/TCD/TCD). TOGA Oil Standard Test mix with 2 Channel detection (FID and TCD) INDUSTRIAL KEY MARKETS Petrochemical and Refinery Gas Analysis INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTFOIL/GOIL In service lubricant testing laboratories analyze millions of samples each year to monitor engine health and prevent costly equipment failures. Detecting fuel and glycol contamination in engine oils is critical for identifying leaks, degraded fluids, and potential engine damage early. Using the Clarus Nova GC, laboratories can perform high throughput FOIL (Fuel in Oil) and GOIL (Glycol in Oil) testing with reliable and repeatable results. The automated workflow with the HS 2400 M Headspace Sampler (GOIL analysis) enables efficient screening of large sample volumes while maintaining analytical accuracy. Benefits: • Detect fuel contamination in engine oils with FOIL workflows • Identify glycol contamination from coolant leaks or gasket failures • High throughput headspace testing for lubricant analysis labs • Reliable quantification of ethylene and propylene glycol in used oils • Supports ASTM D2982, D4291, and D7922 glycol in oil testing methods INDUSTRIAL KEY MARKETS APPLICATIONS & RESOURCES EG in Engine Oil Calibration Diesel in Oil Calibration mix INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTAPPLICATIONS & RESOURCES PerkinElmer Clarus Nova GC solutions are purpose-built for pharmaceutical laboratories where data integrity, method reproducibility, and regulatory readiness are essential to every result. This integrated GC platform supports residual solvent testing, impurity profiling, and stability workflows with validated, traceable performance, helping labs maintain inspection readiness, streamline method transfer across sites, and deliver reliable results from development through routine QC. Pharmaceutical Lab Benefits & Compliance: • Optimized Headspace Analysis: HS 2400™ M headspace autosampler enables reliable, automated residual solvent testing with minimal manual intervention • Inspection-Ready Workflows: Automated checks and secure records support regulated environments • Efficient QC Throughput: Dual injection and fast ovens speed routine testing • Seamless Method Alignment: Consistent performance across instruments and global sites • Analytical Versatility: Detector flexibility supports diverse pharmaceutical applications • Adaptable for Evolving Requirements: Configurable platform supports changing methods and standards PHARMACEUTICAL KEY MARKETS Analysis of Class 2A Residual Solvents According to USP 467* *Data collected on the GC 2400 and the Clarus Nova GC can support this application Analysis of Benzene in Compliance to USP Grade Carbomer 940* INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTAPPLICATIONS & RESOURCES *Data collected on the GC 2400 and the Clarus Nova GC can support this application FOOD AND BEVERAGES KEY MARKETS Fatty Acid Methyl Esters testing in Chicken Powder extracts* Ethanol content in beverages:- (A) and (B) Calibration standards, and (C) Low-level standard (S/N) Chromatograms* PerkinElmer Clarus Nova GC solutions are designed for food safety laboratories balancing high sample volumes with strict regulatory and quality requirements. This flexible GC platform supports volatile analysis, contaminant screening, and packaging gas testing across diverse food matrices, helping labs deliver reliable results quickly, maintain audit readiness, and adapt to evolving food safety standards without workflow disruption. Food Lab Benefits & Assurance: • Audit-Ready Confidence: Built-in controls support global food safety requirements • Faster Sample Turnaround: Headspace automation and DSI accelerate routine testing • Reliable Results Across Matrices: Stable baselines reduce reruns and rework • Flexible Detection Options: Multiple detectors support diverse food analyses • Ready for Changing Standards: Configurable design adapts to new methods INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTAPPLICATIONS & RESOURCES *Data collected on the GC 2400. But the Clarus Nova can support this application ENVIRONMENTAL KEY MARKETS TIC chromatogram of the 86 pesticides at 10 μg/mL standard* Excellent peak shapes of critical compounds demonstrating industry-leading sample flow path inertness* PerkinElmer Clarus Nova GC solutions are built for environmental laboratories delivering fast, defensible data under evolving regulatory and sustainability pressures. This adaptable GC platform supports air, water, and soil testing with reliable trace-level detection and audit-ready performance, helping labs meet compliance requirements, increase sample throughput, and maintain confidence in results across diverse monitoring programs. Environmental Lab Benefits & Compliance: • Regulatory-Ready Operation: Designed to support global environmental standards and audits • High-Volume Sample Throughput: DSI and fast ovens accelerate monitoring workflows • Trace-Level Detection Confidence: Sensitive detection for VOCs and pollutant analysis • Versatile Analytical Coverage: Multiple detectors support diverse environmental methods • Sustainable, Efficient Operation: Energy-saving design supports green lab initiatives INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTAsset Management Asset Utilization Compliance & Validation Lab IT Scientific Services Insights & Analytics Optimize usage, prevent overspend, and improve equipment availability. Turn instrument data into actionable insights. Reduce waste, cut downtime and optimize every square foot of lab space. Stay audit-ready and reduce risk with harmonized documentation. Support scientific computing infrastructure and validated systems. Delegate routine tasks and boost scientific output with onsite professionals. Real-time asset insights and utilization metrics. Optimize spend, streamline operations and maximize scientific output. Integrated Laboratory & Manufacturing Solutions OneSource Digital OneSource offers a comprehensive suite of solutions for laboratories, manufacturing facilities, and capital projects to accelerate the development and commercialization of innovative therapies. Connected Platform – Unifies instruments, software, and services for streamlined lab operations. Instant Visibility – Real-time performance and compliance monitoring across your lab. Predictive Insights – Advanced analytics to reduce downtime and optimize resources. Regulatory Compliance – Secure data handling with audit trails and documentation. Remote Support – Proactive troubleshooting and expert assistance anytime. Scalable Solution – Grows with your lab and supports multi-site connectivity. INTRODUCTION INSTRUMENT OVERVIEW TECHNOLOGY SOFTWARE SUPPORT APPLICATIONS CONTACTClarus® Nova GC For more information visit contact.perkinelmer.com/clarusnova-gc PerkinElmer U.S. LLC 710 Bridgeport Ave. Shelton, CT 06484-4794 USA