The brave new world of immuno-oncology

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Essen Bioscience

For the body to defend and fight against cancer, immune cells must recognize, engage, destroy and ultimately remove unwanted tumor cells. Understanding these processes at the cellular level is central to identifying and validating new immunotherapy approaches. Current methods for studying immune/tumor cell interactions are often end point, require cell lifting or measure indirect readouts meaning valuable data may be overlooked or compromised . Continuous live-cell analysis enables a new range of non-invasive phenotypic measurements for immuno-oncology research including: Immune cell activation, chemotaxis and transendothelial migration Tumor cell proliferation and metastatic potential Immune cell killing of tumor cells and clearance by phagocytosis