Pharmaceutical quality control laboratories often run assay and impurity testing as separate chromatography workflows, creating instrument bottlenecks, limiting throughput, and increasing solvent consumption.
Newer liquid chromatography systems allow both analyses to run together in a single method, helping laboratories process more samples while using fewer resources.
This infographic shows how one laboratory reduced total analysis time from 60 minutes to 5.5 minutes, increasing throughput and laboratory capacity while supporting sustainability goals.
Download this infographic to explore how:
- A consolidated workflow cuts analysis time from 60 minutes to 5.5 minutes
- Larger sample capacity and faster cycles help increase throughput
- Reduced solvent use lowers costs and laboratory waste
~5.5 L
of solvents
used per
sequence*
“Vanquish systems have proven to
be robust and have not led to any
system suitability failures.”
!
!
1Yearly savings from 300 lots
2Assuming a 7.5-hour workday
and only 25% of daily activities
associated with HPLC
Sanofi, an innovative global healthcare company, began modernizing its
LC methods using Thermo Scientific™ Vanquish™ LC systems to improve
throughput. This upgrade increased capacity and lowered their environmental
impact through a reduction in energy and solvent consumption.
Estimated savings
106 days of run time
109 L of solvents
saved per year
20 analyst workdays
saved per year
Solvent
consumption
Time
AFTER
BEFORE
2 hrs.
and 57 min.
13 hrs.
and 35 min.
AFTER
BEFORE
0.13 L
1.2 L
Accelerating your lab operations
with Vanquish LC systems
Give your lab a boost
Learn more about
cost of ownership
5.5 min.
~3.0 L
of solvents used
per sequence*
~2.5 L
total savings
Benefits:
BEFORE AFTER
Learn more
about cost of
ownership
Meet your
dream HPLC
system today
Learn how to
increase your
productivity
For Research Use Only. Not for use in diagnostic procedures. © 2023-2024 Thermo Fisher Scientific Inc. All rights reserved.
All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. IN003058 1024
Learn more at thermofisher.com/methodmodernization
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15 min.
assay method
run time
+
45 min.
impurity method
run time
60 min.
total run time
combined assay/
impurity method
run time
*Sequence = 3 batches
and 10 content
uniformity. Includes
the sample prep
solvent usage.
• Shorter injection cycle time
(1 min. vs. 2.5 min.)
• Larger sample capacity
(216 x 2 mL vials)
Modernizing your LC systems
can help you:
Lower power
consumption
Lower solvent
usage
• 5.5 min. vs. 60 min. per analysis
• 78% reduction in instrument run
time per sequence
• Save on instrument running and
solvent waste disposal costs
• 2.5 fewer liters per
sequence
• Save over $10,000
per year
Yearly savings1
LC analysis time (workday)
Solvent consumption (L)
20
109
Labor (USD)2
Solvent (USD)
$3,800
$3,270
Saves approximately $7,000 per year in labor and solvent
consumption/disposal
If you’re looking to maximize efficiency, explore Thermo Scientific
Vanquish Duo UHPLC systems.
• Two complete HPLC systems in a single stack
• Reduce your costs: Lower investment and maintenance costs
vs. two individual systems
• Increase capacity without the need for additional bench space
Cut your labor costs
Double your throughput
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Method modernization
Vanquish technology benefits
Boosting your productivity
Meet your sustainability goals
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