In a typical chromatographic analysis, sample preparation is the most labor-intensive and error-prone step.
Automated liquid handling technologies can help to save time and increase reproducibility, which is key to achieving precise and accurate results.
This infographic highlights cutting-edge automated sample handling systems and software that are easy to use for both novices and experts.
Download this infographic to explore:
• The benefits of liquid handling automation
• Automated systems that can be integrated in any lab
• User-friendly software to easily create new workflows
Automated liquid handling technologies help increase reproducibility during sample preparation,
which is key to achieve precise and accurate results. Modern automated systems are compact and
modular and can be integrated in any lab. Moreover, they can be controlled by user-friendly software,
allowing researchers to create new workflows easily. This infographic explores the benefits of
automation and presents cutting-edge automated sample handling systems that are easy to use
for both novices and experts.
The benefits of automation
Flexible sample handling solutions
In a typical liquid or gas chromatography analysis (e.g., LC/MS or GC/MS), sample preparation is the
most labor intensive and error prone step.1
Laboratories looking to maximize throughput and minimize costs per sample have incorporated the
PAL System into their workflows. This sample preparation and handling platform is used worldwide
for anything from simple liquid injection to complete workflow automation.
Typical chromatographic analysis
Automation helps you to
Modules to meet any need: Tools for every application:
• Liquid tools µL–mL
• GC-headspace tools
• Barcode reader
• Heatex stirrer
• SPME Arrow
• Vortex mixer
• Liquid injection GC and LC
• Gas injection
• Headspace sampling
• Dynamic headspace sampling (ITEX DHS)
• SPME and SPME Arrow sampling
• Temperature controlled sample storage
• Incubation 40 - 200 °C
• Tool change (PAL RTC only)
• Transport of vials and other objects
• Vortex mixing
• Centrifugation up to 5000 g
• Standard addition
• Liquid/liquid extraction (LLE)
• Micro-SPE (μSPE)
• Wash stations
• Solvent addition µL–L
• Storage of vials and
PAL System capabilities
How can I easily program the
PAL System and create sample prep
workflows for my different experiments?
The PAL Method Composer
(PMC) is the answer!
Faster sample preparation
The PAL Method Composer (PMC) is an intuitive software that offers direct access to all the PAL
System’s capabilities. By simply dragging and dropping the individual prep steps, this user-friendly
interface allows you to quickly develop and test customized methods which can then be imported
and used directly in a wide list of Chromatographic Data Systems (CDS) or MS-Data Systems.
Drag and drop
Easy to use
Module top view pane
It shows six categories of steps that can be
dragged and dropped into the method pane.
It shows the real configuration of all active
and passive PAL modules.
It shows the sequence of steps. Each
step can be moved to another position
within the method using drag and
drop. The parameters for each step
can be adjusted.
Can be integrated with any GC-MS or LC-MS system
● Steps for PAL System µSPE workflows
● Easy adaption of methods for transfer between different PAL Systems
● PMC currently supports the following CDS and MS-Data Systems
● More flexibility using tokens (variables for values that change with any
sample in the sequence table e.g., sample volume, sample position)
● Coming soon: SCIEX OS
1. Sample preparation fundamentals for chromatography. Agilent Technologies. https://www.agilent.com/cs/library/
primers/Public/5991-3326EN_SPHB.pdf. Accessed June 6, 2023.
Further features of the PMC include:
• Agilent: ChemStation / MassHunter / OpenLAB
• Bruker: Compass HyStar
• SCIEX: Analyst AAO and ADD
• Shimadzu: GCMSsolution Software / LabSolutions
• Thermo: Xcalibur / Chromeleon / TraceFinder
• Waters: Empower 3
Download your free trial version and
create new methods in minutes
Time Sources of error
It shows all modules
and tools available in
the configuration of the
connected PAL System.
Removing Stumbling Blocks in
Automated Sample Preparation
reproducibility Save time Increase