We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.


Top-down vs. Bottom-up Proteomics

Top-down vs. Bottom-up Proteomics content piece image

Proteomics is an essential tool for the diagnosis, prognosis, and development of disease – since most diseases manifest at the protein activity level. In addition, it also plays a crucial role in drug discovery and development, helping to identify potential therapeutic targets.

The ’bottom-up’ approach has historically been the most commonly used workflow in proteomics, however, more recently the use of ‘top-down’ methods have begun to gain momentum.

Download this infographic to:

  • Review both approaches
  • Learn the main advantages and disadvantages of each approach
  • Discover the applications each approach is best suited for