AB SCIEX and Premier Biosoft Collaborate on Lipidomics Software
News Jun 04, 2012
To offer integrated workflows, AB SCIEX will co-market and resell PREMIER Biosoft's SimLipid, a comprehensive high throughput lipid identification software product, for use with AB SCIEX's wide range of mass spectrometers.
SimLipid profiles lipids present in a sample by performing precursor search for MS data and elucidates the structures by matching product ions observed on the MS/MS spectra.
A proprietary probability score is assigned to each of the candidate lipid structure. This score is especially designed for discriminating isomers with similar m/z.
It is calculated according to the best fit of the experimental m/z values with the theoretical m/z values of both precursor and fragment ions of the SimLipid database.
SimLipid is capable of analyzing both low resolution data as well as high resolution data. For low resolution data, SimLipid performs isotopic peak correction to remove isotope overlapping of lipid species.
Interpretation of MS and MS/MS spectra have been made easy by annotating matched peaks with corresponding lipids and fatty acid chains.
In addition, each structure is mined for associated class, reaction, pathway and enzyme, saving users their valuable time, money and the frustration of laborious manual annotation.
According to Kay Brown, President at PREMIER Biosoft, "We are pleased to expand PREMIER Biosoft's collaborative relationship with AB SCIEX that started with glycomics with SimGlycan® to lipidomics with SimLipid. Combining AB SCIEX's mass spectrometry data with SimLipid creates an opportunity for researchers to gain access to unparalleled information for lipid characterization."
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