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Cryo-EM Imaging Suggests How the Double Helix Separates During Replication

News   Oct 24, 2017 | Original Story by Peter Tarr for Cold Spring Harbor Laboratory.

 
Cryo-EM Imaging Suggests How the Double Helix Separates During Replication

The DNA double helix follows a zig-zag path inside a channel created by two 6-sided rings. This new atomic-level view made with cryo-EM technology, suggests how DNA interacts with the two rings just prior to being separated into "leading" and "lagging" strands. All life depends on absolutely precise choreography, when one cell beings to replicate its DNA in order to make two cells. Credit: Van Andel Research Institute.

 
 
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