We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.


Detecting Hidden Ingredients

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "Detecting Hidden Ingredients "

First Name*
Last Name*
Email Address*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Read time:

To lose weight, boost energy or soothe nerves, many consumers turn to dietary supplements. But some of these products contain undeclared substances. To protect consumers from taking something without their knowledge, scientists have developed a technique to determine what secret ingredients could be lurking in these supplements. They report their approach, which helped them find the active Viagra ingredient and other synthetic designer compounds in various products. 

Dietary supplements can appear to be a healthful option for treating certain health conditions. Their labels list herbs or other natural ingredients that consumers assume are safe to take. But over the past several years, regulators have detected prohibited substances in some of these products that aren't included on the labels. The drug sibutramine is one of these substances. It was once approved for weight loss but was withdrawn after concerns arose that the medication could increase the risk of heart attacks. To catch supplements spiked with sibutramine and other undeclared substances, Zhiqiang Huang, Bin Guo and colleagues came up with a strategy.

Using an advanced liquid chromatography-mass spectrometry screening procedure, the researchers tested more than 100 syrups, capsules and other types of supplements purchased in markets in China and online. The products' labels claimed benefits from blood pressure reduction to enhanced sexual performance. Their approach successfully detected a wide range of targeted adulterants -- including sibutramine and sildenafil, the active ingredient in Viagra -- and other unexpected drug compounds.